Antigens, Differentiation, T-Lymphocyte - Metabolism
Research News and Information

Tuesday, November 24, 2009

Primary human tumor cells expressing CD155 impair tumor targeting by down-regulating DNAM-1 on NK cells.

13 Oct 2009 The activating NK cell receptor DNAX accessory molecule-1 (DNAM-1) contributes to tumor immune surveillance and plays a crucial role in NK cell-mediated recognition of several types of human tumors, including ovarian carcinoma. Here, we have ... Read more...

Genetic evidence that the differential expression of the ligand-independent isoform of CTLA-4 is the molecular basis of the Idd5.1 type 1 diabetes region in nonobese diabetic mice.

23 Sep 2009 Idd5.1 regulates T1D susceptibility in nonobese diabetic (NOD) mice and has two notable candidate genes, Ctla4 and Icos. Reduced expression of one of the four CTLA-4 isoforms, ligand-independent CTLA-4 (liCTLA-4), which inhibits in vitro T cell ... Read more...

Domain analyses of the Runx1 transcription factor responsible for modulating T-cell receptor-beta/CD4 and interleukin-4/interferon-gamma expression in CD4(+) peripheral T lymphocytes.

30 Aug 2009 The Runx1 transcription factor is one of the master regulators of T-lymphocyte differentiation. There have been several reports trying to assign a domain within the Runx1 protein that is responsible for gene expression in thymocytes. The Runx1 ... Read more...

Latest indexed articles for 'Antigens, Differentiation, T-Lymphocyte - Metabolism'

These are the very latest articles for this heading:

• Primary human tumor cells expressing CD155 impair tumor targeting by down-regulating DNAM-1 on NK cells. 13 Oct 2009
• Genetic evidence that the differential expression of the ligand-independent isoform of CTLA-4 is the molecular basis of the Idd5.1 type 1 diabetes region in nonobese diabetic mice. 23 Sep 2009
• Domain analyses of the Runx1 transcription factor responsible for modulating T-cell receptor-beta/CD4 and interleukin-4/interferon-gamma expression in CD4(+) peripheral T lymphocytes. 30 Aug 2009
• IL-10 production by B cells expressing CD5 with the alternative exon 1B. 30 Aug 2009
• Dynamic accumulation of plasmacytoid dendritic cells in lymph nodes is regulated by interferon-beta. Aug 2009
• In vitro tests in drug hypersensitivity diagnosis. 30 Jul 2009
• Enhanced proliferation and activation of peripheral blood mononuclear cells in patients with psoriasis vulgaris mediated by streptococcal antigen with bacterial DNA. 14 Jul 2009
• Reverse signaling using an inducible costimulator to enhance immunogenic function of dendritic cells. 13 Jul 2009
• Exposure to cigarette smoke suppresses IL-15 generation and its regulatory NK cell functions in poly I:C-augmented human PBMCs. 7 Jul 2009
• Cryopreservation of monocytes is superior to cryopreservation of immature or semi-mature dendritic cells for dendritic cell-based immunotherapy. 29 Jun 2009
• The fate of human Treg cells. 17 Jun 2009
• Airway hyperresponsiveness is associated with activated CD4+ T cells in the airways. 27 May 2009
• Natural killer cell functional dichotomy in chronic hepatitis B and chronic hepatitis C virus infections. 22 May 2009
• The role of costimulation in antibody deficiencies: ICOS and common variable immunodeficiency. 29 Apr 2009
• CD28 and CTLA-4 coreceptor expression and signal transduction. 29 Apr 2009
• Mechanisms of costimulation. 29 Apr 2009
• Follow-up study of immune defects in patients with dysmorphic disorders. 29 Apr 2009
• Impaired CD4 and CD8 effector function and decreased memory T cell populations in ICOS-deficient patients. 29 Apr 2009
• Heterogeneous expression of the adhesion receptor CD226 on murine NK and T cells and its function in NK-mediated killing of immature dendritic cells. 18 Apr 2009
• Gene expression profiling reveals differences in microenvironment interaction between patients with chronic lymphocytic leukemia expressing high versus low ZAP70 mRNA. 16 Apr 2009

See a longer list of these articles.

Technical information about 'Antigens, Differentiation, T-Lymphocyte'

Definition: Antigens expressed on the cell membrane of T-lymphocytes during differentiation, activation, and normal and neoplastic transformation. Their phenotypic characterization is important in differential diagnosis and studies of thymic ontogeny and T-cell function.

Registry Number: 0

Descriptor UI: D000945

Alternative terms: Antigens, Differentiation, T-Lymphocyte; T-Cell Differentiation Antigens; Antigens, T-Cell Differentiation; T Cell Differentiation Antigens; Differentiation Antigens, T-Cell; Differentiation Antigens, T Cell; Leu Antigens, T-Lymphocyte; Antigens, T-Lymphocyte Leu; Leu Antigens, T Lymphocyte; T-Lymphocyte Leu Antigens; Differentiation Antigens, T Lymphocyte; T-Lymphocyte Differentiation Antigens; Antigens, T-Lymphocyte Differentiation; Differentiation Antigens, T-Lymphocyte; T Lymphocyte Differentiation Antigens; Antigens, Differentiation, T-Cell; Antigens, Differentiation, T Lymphocyte; L3T4 Antigens; Antigens, L3T4; T6 Antigens; Antigens, T6;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; biosynthesis; blood; cerebrospinal fluid; classification; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacology; physiology; poisoning; radiation effects; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications;

Tree Number: D23.050.301.264.894; D23.101.100.894;

Online Note: use ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE to search T8 ANTIGENS 1988-92 & ANTIGENS, DIFFERENTIATION T LYMPHOCYTE 1988-89

History Note: 90; was ANTIGENS, DIFFERENTIATION, T LYMPHOCYTE 1988-89; T8 ANTIGENS was see ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1988-92

Technical Notes: DF: T CELL DIFFER ANTIGENS