Antigens, Differentiation
Research News and Information

Sunday, November 22, 2009

Acquisition of T regulatory function in cathepsin L-inhibited T cells by eye-derived CTLA-2alpha during inflammatory conditions.

13 Oct 2009 Pigment epithelium isolated from the eye possesses immunosuppressive properties such as regulatory T (Treg) cell induction; e.g., cultured retinal pigment epithelium (RPE) converts CD4(+) T cells into Treg cells in vitro. RPE constitutively ... Read more...

Highly sensitive multivariable assay detection of melanocytic differentiation antigens and angiogenesis biomarkers in sentinel lymph nodes with melanoma micrometastases.

29 Sep 2009 OBJECTIVES: To evaluate the prognostic value of melanocytic differentiation antigens and angiogenesis biomarkers in sentinel lymph nodes (SLNs) with melanoma micrometastases. DESIGN: Prognostic study of an inception cohort. SETTING: Academic ... Read more...

Human defensins activate monocyte-derived dendritic cells, promote the production of proinflammatory cytokines, and up-regulate the surface expression of CD91.

29 Sep 2009 Defensins are endogenous defense peptides with well defined antimicrobial activity against a broad spectrum of pathogens including bacteria, fungi, viruses, and parasites.Several lines of evidence suggest that defensins might also contribute to the ... Read more...

Latest indexed articles for 'Antigens, Differentiation'

These are the very latest articles for this heading:

• Acquisition of T regulatory function in cathepsin L-inhibited T cells by eye-derived CTLA-2alpha during inflammatory conditions. 13 Oct 2009
• Highly sensitive multivariable assay detection of melanocytic differentiation antigens and angiogenesis biomarkers in sentinel lymph nodes with melanoma micrometastases. 29 Sep 2009
• Human defensins activate monocyte-derived dendritic cells, promote the production of proinflammatory cytokines, and up-regulate the surface expression of CD91. 29 Sep 2009
• Phenotypic characterization of distinct human bone marrow-derived MSC subsets. 30 Aug 2009
• Obesity accelerates thymic aging. 29 Aug 2009
• Characterisation of myeloid receptor expression and interferon alpha/beta production in murine plasmacytoid dendritic cells by flow cytomtery. 5 Aug 2009
• The basophil activation test in immediate-type drug allergy. 30 Jul 2009
• Platelet-derived growth factor-receptor alpha strongly inhibits melanoma growth in vitro and in vivo. 30 Jul 2009
• Isolation of dendritic cells. 30 Jul 2009
• Castleman's disease with numerous mantle zone lymphocytes with clear cytoplasm involving the skin: case report. 30 Jul 2009
• Structure of signal-regulatory protein alpha: a link to antigen receptor evolution. 21 Jul 2009
• Enterococcus faecalis translocation in mice with severe burn injury: a pathogenic role of CCL2 and alternatively activated macrophages (M2aMphi and M2cMphi). 19 Jul 2009
• Deltex1 is a target of the transcription factor NFAT that promotes T cell anergy. 15 Jul 2009
• Turn-over of meningeal and perivascular macrophages in the brain of MCP-1-, CCR-2- or double knockout mice. 13 Jul 2009
• Hematopoietic stem cell origin of adipocytes. 30 Jun 2009
• Endocardial cells are a distinct endothelial lineage derived from Flk1+ multipotent cardiovascular progenitors. 29 Jun 2009
• Role of ocular pigment epithelial cells in immune privilege. 29 Jun 2009
• Effects of pharmacological inhibition and genetic deficiency of plasminogen activator inhibitor-1 in radiation-induced intestinal injury. 29 Jun 2009
• Interaction of programmed death-1 and programmed death-1 ligand-1 contributes to testicular immune privilege. 25 Jun 2009
• HPV16 tumor associated macrophages suppress antitumor T cell responses. 21 Jun 2009

See a longer list of these articles.

Technical information about 'Antigens, Differentiation'

Definition: Antigens expressed primarily on the membranes of living cells during sequential stages of maturation and differentiation. As immunologic markers they have high organ and tissue specificity and are useful as probes in studies of normal cell development as well as neoplastic transformation.

Registry Number: 0

Descriptor UI: D000943

Alternative terms: Antigens, Differentiation; Differentiation Markers; Markers, Differentiation; Differentiation Antigens; Marker Antigens; Antigens, Marker; Leu Antigens; Antigens, Leu; Differentiation Antigens, Hairy Cell Leukemia;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; biosynthesis; blood; cerebrospinal fluid; classification; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacology; physiology; poisoning; radiation effects; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications;

Tree Number: D23.050.301.264; D23.101.100;

Online Note: use ANTIGENS, DIFFERENTIATION, B-LYMPHOCYTE to search DIFFERENTIATION ANTIGENS, HAIRY CELL LEUKEMIA 1988-91; use ANTIGENS, DIFFERENTIATION to search LEU ANTIGENS 1989 to present; use ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1988

History Note: 88; DIFFERENTIATION ANTIGENS, HAIRY CELL LEUKEMIA was see ANTIGENS, DIFFERENTIATION, B-LYMPHOCYTE 1988-91; LEU ANTIGENS was see ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1988

Technical Notes: GEN: prefer specific groups & specific differentiation antigens; note X ref LEU ANTIGENS but several specific Leu antigens are also available; DF: ANTIGENS DIFFER