Antimalarials - Research News and Information

Wednesday, January 07, 2009

A randomized, controlled trial of intermittent preventive treatment with sulfadoxine-pyrimethamine, amodiaquine, or the combination in pregnant women in Ghana.

13 Oct 2008 BACKGROUND: The use of sulfadoxine-pyrimethamine (SP) for intermittent preventive treatment in pregnancy (IPTp) is threatened by the spread of resistance to SP. Therefore, we studied the efficacy, safety, and tolerance of amodiaquine (AQ) or the ... Read more...

Impact of training in clinical and microscopy diagnosis of childhood malaria on antimalarial drug prescription and health outcome at primary health care level in Tanzania: a randomized controlled trial.

30 Sep 2008 BACKGROUND: Prescribing antimalarial medicines based on parasite confirmed diagnosis of malaria is critical to rational drug use and optimal outcome of febrile illness. The impact of microscopy-based versus clinical-based diagnosis of childhood ... Read more...

Retinal toxicity of chloroquine hydrochloride administered by intraperitoneal injection.

29 Sep 2008 Chloroquine is quinolone derivative known to exert dose-related retinal toxicity, albeit in a variable manner. It is thought that variability in the presentation of chloroquine retinopathy may be the result of perturbations in drug bioavailability ... Read more...

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Latest indexed articles for 'Antimalarials'

These are the very latest articles for this heading:

• Intermittent preventive antimalarial treatment in infancy. 16 Oct 2008
• A randomized, controlled trial of intermittent preventive treatment with sulfadoxine-pyrimethamine, amodiaquine, or the combination in pregnant women in Ghana. 13 Oct 2008
• Infectious disease. New malaria plan called ambitious by some, unrealistic by others. Oct 2008
• Impact of training in clinical and microscopy diagnosis of childhood malaria on antimalarial drug prescription and health outcome at primary health care level in Tanzania: a randomized controlled trial. 30 Sep 2008
• Retinal toxicity of chloroquine hydrochloride administered by intraperitoneal injection. 29 Sep 2008
• Drug interactions involving combination antiretroviral therapy and other anti-infective agents: repercussions for resource-limited countries. 29 Sep 2008
• Molecular surveillance for multidrug-resistant Plasmodium falciparum, Cambodia. 29 Sep 2008
• Clinical Pharmacology of Antimalarial Drugs--First AHRO International Malaria Symposium. 29 Sep 2008
• Malarial chemoprophylaxis. 29 Sep 2008
• Genetic evidence for Plasmodium falciparum resistance to chloroquine and pyrimethamine in Indochina and the Western Pacific between 1984 and 1998. 29 Sep 2008
• Pharmacokinetics of the antimalarial drug piperaquine in healthy Vietnamese subjects. 29 Sep 2008
• Depsipeptides from microorganisms: a new class of antimalarials. 29 Sep 2008
• Costs and cost-effectiveness of delivering intermittent preventive treatment through schools in western Kenya. 28 Sep 2008
• Effectiveness of artemisinin-based combination therapy used in the context of home management of malaria: a report from three study sites in sub-Saharan Africa. 25 Sep 2008
• Comprehensive study of proteasome inhibitors against Plasmodium falciparum laboratory strains and field isolates from Gabon. 22 Sep 2008
• Epidemiology. Lower malaria numbers reflect better estimates and a glimmer of hope. 17 Sep 2008
• Malaria case-management under artemether-lumefantrine treatment policy in Uganda. 17 Sep 2008
• A community effectiveness trial of strategies promoting intermittent preventive treatment with sulphadoxine-pyrimethamine in pregnant women in rural Burkina Faso. 16 Sep 2008
• WHO report shows progress in efforts to reduce malaria incidence. 15 Sep 2008
• Fixed-dose pyronaridine-artesunate combination for treatment of uncomplicated falciparum malaria in pediatric patients in Gabon. 13 Sep 2008

See a longer list of these articles.

Technical information about 'Antimalarials'

Definition: Agents used in the treatment of malaria. They are usually classified on the basis of their action against plasmodia at different stages in their life cycle in the human. (From AMA, Drug Evaluations Annual, 1992, p1585)

Registry Number: 0

Descriptor UI: D000962

Alternative terms: Antimalarials; Anti-Malarials; Anti Malarials; Antimalarial Agents; Agents, Antimalarial; Antimalarial Drugs; Drugs, Antimalarial;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D27.505.954.122.250.100.085;