Antimicrobial Cationic Peptides - Research News and Information

Thursday, January 08, 2009

An exceptional salt-tolerant antimicrobial peptide derived from a novel gene family of haemocytes of the marine invertebrate Ciona intestinalis.

13 Nov 2008 A novel gene family coding for putative antimicrobial peptides was identified in the EST (expressed sequence tag) database of the sea squirt Ciona intestinalis, and one of these genes was molecularly cloned from the Northern European Ciona ... Read more...

Hepatitis C virus-induced oxidative stress suppresses hepcidin expression through increased histone deacetylase activity.

30 Oct 2008 Chronic hepatitis C is characterized by iron accumulation in the liver, and excessive iron is hepatotoxic. However, the mechanism by which hepatitis C virus (HCV) regulates iron metabolism is poorly understood. Hepcidin plays a pivotal role as a ... Read more...

Cytokine-mediated regulation of antimicrobial proteins.

30 Oct 2008 Antimicrobial proteins constitute a phylogenetically ancient form of innate immunity that provides host defence at skin and mucosal surfaces. Although some components of this system are constitutively expressed, new evidence reviewed in this ... Read more...

Learn Faster Today      Improve your study skills

Latest indexed articles for 'Antimicrobial Cationic Peptides'

These are the very latest articles for this heading:

• An exceptional salt-tolerant antimicrobial peptide derived from a novel gene family of haemocytes of the marine invertebrate Ciona intestinalis. 13 Nov 2008
• Hepatitis C virus-induced oxidative stress suppresses hepcidin expression through increased histone deacetylase activity. 30 Oct 2008
• Cytokine-mediated regulation of antimicrobial proteins. 30 Oct 2008
• Antineutrophil cytoplasmic autoantibodies: how should the biologist manage them? 29 Sep 2008
• Efficacy of LL-37 and granulocyte colony-stimulating factor in a neutropenic murine sepsis due to Pseudomonas aeruginosa. 29 Sep 2008
• Alpha-defensin-like product and asymmetric dimethylarginine increase in mesenteric lymph after hemorrhage in anesthetized rat. 29 Sep 2008
• Mode of action of antimicrobial peptide P45 on Listeria monocytogenes. 29 Sep 2008
• Fungicidal effect of piscidin on Candida albicans: pore formation in lipid vesicles and activity in fungal membranes. 29 Sep 2008
• Gene symbol: HAMP. Disease: Haemochromatosis, juvenile. 29 Sep 2008
• Branched peptides as therapeutics. 29 Sep 2008
• Molecular basis for proline- and arginine-rich peptide inhibition of proteasome. 14 Sep 2008
• Cathelicidin antimicrobial peptides inhibit hyaluronan-induced cytokine release and modulate chronic allergic dermatitis. 13 Sep 2008
• Folding propensity and biological activity of peptides: the effect of a single stereochemical isomerization on the conformational properties of bombinins in aqueous solution. 30 Aug 2008
• Efficacy of the amphibian peptide distinctin in a neutropenic mouse model of staphylococcal sepsis. 30 Aug 2008
• Monitoring the interference of protein-protein interactions in vivo by bimolecular fluorescence complementation: the DnaK case. 30 Aug 2008
• Quantification of hepcidin-25 in human serum by isotope dilution micro-HPLC-tandem mass spectrometry. 30 Aug 2008
• Serum pro-hepcidin level and iron homeostasis in Japanese dialysis patients with erythropoietin (EPO)-resistant anemia. 30 Aug 2008
• The role of antimicrobial peptides in human skin and in skin infectious diseases. 30 Aug 2008
• Potential roles of histones in host defense as antimicrobial agents. 30 Aug 2008
• The use of technetium-99m radiolabeled human antimicrobial peptides for infection specific imaging. 30 Aug 2008

See a longer list of these articles.

Technical information about 'Antimicrobial Cationic Peptides'

Definition: Small cationic peptides that are an important component, in most species, of early innate and induced defenses against invading microbes. In animals they are found on mucosal surfaces, within phagocytic granules, and on the surface of the body. They are also found in insects and plants. Among others, this group includes the DEFENSINS, protegrins, tachyplesins, and thionins. They displace DIVALENT CATIONS from phosphate groups of MEMBRANE LIPIDS leading to disruption of the membrane.

Registry Number: 0

Descriptor UI: D023181

Alternative terms: Antimicrobial Cationic Peptides; Cationic Peptides, Antimicrobial; Peptides, Antimicrobial Cationic; Microbicidal Cationic Proteins; Cationic Proteins, Microbicidal; Proteins, Microbicidal Cationic; Cationic Antimicrobial Peptides; Antimicrobial Peptides, Cationic; Peptides, Cationic Antimicrobial; Amphipathic Cationic Antimicrobial Peptides;

Related Mesh Headings: Blood Bactericidal Activity;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Anti-Infective Agents;

Tree Number: D12.644.050; D12.776.543.695.054;

History Note: 2001; use ANTIMICROBIAL CATIONIC PEPTIDES (NM) to search MICROBICIDAL CATIONIC PROTEINS 1981-2000