Antineoplastic Agents, Phytogenic - Pharmacology
Research News and Information

Saturday, November 21, 2009

Fern plant-derived protoapigenone leads to DNA damage, apoptosis, and G(2)/m arrest in lung cancer cell line H1299.

29 Sep 2009 Protoapigenone, isolated from the native fern plant Thelypteris torresiana, has anticancer activity against some cancer cells. However, the toxicological mechanism for protoapigenone is still unknown. Here, we investigated the anticancer effect of ... Read more...

Benefits of drug-eluting stents as compared to bare metal stent in ST-segment elevation myocardial infarction: four year results of the PaclitAxel or Sirolimus-Eluting stent vs bare metal stent in primary angiOplasty (PASEO) randomized trial.

29 Sep 2009 BACKGROUND: Drug-eluting stent (DES) may offer benefits in terms of repeat revascularization, which may be counterbalanced by a potential higher risk of stent thrombosis, especially among patients with STEMI. No data have been reported so far on the ... Read more...

Amplification of the ABCB1 region accompanied by a short sequence of 200bp from chromosome 2 in lung cancer cells.

29 Sep 2009 Lung cancer sublines No15-80-1 and No15-80-6 were selected by treatment of cell line NCI-H460 with paclitaxel at stepwise increasing concentrations from 50 nmol/L to 800 nmol/L. The two sublines exhibited amplifications of the ABCB1 region ... Read more...

Latest indexed articles for 'Antineoplastic Agents, Phytogenic - Pharmacology'

These are the very latest articles for this heading:

• Fern plant-derived protoapigenone leads to DNA damage, apoptosis, and G(2)/m arrest in lung cancer cell line H1299. 29 Sep 2009
• Benefits of drug-eluting stents as compared to bare metal stent in ST-segment elevation myocardial infarction: four year results of the PaclitAxel or Sirolimus-Eluting stent vs bare metal stent in primary angiOplasty (PASEO) randomized trial. 29 Sep 2009
• Amplification of the ABCB1 region accompanied by a short sequence of 200bp from chromosome 2 in lung cancer cells. 29 Sep 2009
• Novel ceramides from aerial parts of Saussurea involucrata Kar. et. Kir. 24 Sep 2009
• Cytotoxic, cytoprotective and antioxidant activities of resveratrol and analogues in C6 astroglioma cells in vitro. 6 Sep 2009
• Resveratrol suppresses growth of human ovarian cancer cells in culture and in a murine xenograft model: eukaryotic elongation factor 1A2 as a potential target. 6 Sep 2009
• Effect of low-dose Paclitaxel and docetaxel on endothelial progenitor cells. Sep 2009
• Leucophyllidine, a cytotoxic bisindole alkaloid constituted from the union of an eburnan and a new vinylquinoline alkaloid. Sep 2009
• Inhibition of lipid peroxidation, cyclooxygenase enzyme and human tumor cell proliferation by compounds in herbal water. 30 Aug 2009
• Synthetic galectin-3 inhibitor increases metastatic cancer cell sensitivity to taxol-induced apoptosis in vitro and in vivo. 30 Aug 2009
• Alkaloids from the leaves of Daphniphyllum subverticillatum. 30 Aug 2009
• Antiproliferative triterpenoid saponins of Dodonaea viscosa from the Madagascar dry forest. 30 Aug 2009
• Biscarpamontamines A and B, an aspidosperma-iboga bisindole alkaloid and an aspidosperma-aspidosperma bisindole alkaloid, from Tabernaemontana sphaerocarpa. 30 Aug 2009
• Chemical Constituents of the Roots of Euphorbia micractina. 30 Aug 2009
• Influenza A (H(1)N(1)) Antiviral and Cytotoxic Agents from Ferula assa-foetida. 30 Aug 2009
• Cytotoxic constituents of Soymida febrifuga from Myanmar. 30 Aug 2009
• A proteomic study on a human osteosarcoma cell line Saos-2 treated with diallyl trisulfide. 30 Aug 2009
• Erkitinib, a novel EGFR tyrosine kinase inhibitor screened using a ProteoChip system from a phytochemical library. 26 Aug 2009
• The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress. 26 Aug 2009
• SPIRIT IV trial design: a large-scale randomized comparison of everolimus-eluting stents and paclitaxel-eluting stents in patients with coronary artery disease. 24 Aug 2009

See a longer list of these articles.

Technical information about 'Antineoplastic Agents, Phytogenic'

Definition: Agents obtained from higher plants that have demonstrable cytostatic or antineoplastic activity.

Registry Number: 0

Descriptor UI: D000972

Alternative terms: Antineoplastic Agents, Phytogenic; Agents, Phytogenic Antineoplastic; Phytogenic Antineoplastic Agents; Antineoplastics, Phytogenic; Phytogenic Antineoplastics; Antineoplastics, Botanical; Botanical Antineoplastics;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists; biosynthesis;

Tree Number: D27.505.954.248.179;

Online Note: use ANTINEOPLASTIC AGENTS, PHYTOGENIC to search ANTINEOPLASTICS, PHYTOGENIC 1975

History Note: 76; was ANTINEOPLASTICS, PHYTOGENIC 1975

Technical Notes: from plants of Cat B6 only, not from lower plants (Cat B5: algae & fungi); /biosyn permitted if by plant; TN 4: coverage