Antitussive Agents - Administration & dosage
Research News and Information

Monday, November 23, 2009

Discovery of orally active 3-pyridinyl-tropane as a potent nociceptin receptor agonist for the management of cough.

8 Sep 2009 A series of 3-pyridinyl-tropane analogues based on previously reported compound 1 have been synthesized and shown to bind to the nociceptin receptor with high affinity. From the SAR study and our lead optimization efforts, compound 10 was found to ... Read more...

Parental misinterpretations of over-the-counter pediatric cough and cold medication labels.

30 May 2009 OBJECTIVE: Concerns about the safety and efficacy of over-the-counter cold medications have led to a recent US Food and Drug Administration public health advisory against their use in children <2 years of age. Our goal was to examine caregiver ... Read more...

Unclear loss of consciousness after clobutinol intake.

19 May 2009 The case of a 13-month-old boy with a diagnosis of unclear unconsciousness is reported on. As the physical examination did not lead to any explanation of his condition, the administration of drugs in the context of Munchausen syndrome by proxy was ... Read more...

Latest indexed articles for 'Antitussive Agents - Administration & dosage'

These are the very latest articles for this heading:

• Discovery of orally active 3-pyridinyl-tropane as a potent nociceptin receptor agonist for the management of cough. 8 Sep 2009
• Parental misinterpretations of over-the-counter pediatric cough and cold medication labels. 30 May 2009
• Unclear loss of consciousness after clobutinol intake. 19 May 2009
• Addictive evaluation of cholic acid-verticinone ester, a potential cough therapeutic agent with agonist action of opioid receptor. 29 Apr 2009
• Dextromethorphan hydrobromide preparations on the Belgian market--a comparative study. 27 Feb 2009
• Misuse of over-the-counter cough or cold medications among adolescents: prevalence and correlates in a national sample. 2 Jan 2009
• TRPA1: a potential target for anti-tussive therapy. 29 Dec 2008
• Antitussive activity of polysaccharides isolated from the Malian medicinal plants. 23 Dec 2008
• "DXemon juice:" analytical evaluation of an extraction process for the purification and freebasing of dextromethorphan from cold preparations. 29 Nov 2008
• Developing antitussives: the ideal clinical trial. 11 Nov 2008
• Drug dosing error with drops: severe clinical course of codeine intoxication in twins. 19 Oct 2008
• Effect of tiotropium on cough reflex sensitivity in acute viral cough. 10 Sep 2008
• Formulation and evaluation of dextromethorphan hydrobromide sustained release tablets. 30 Aug 2008
• IgE-mediated anaphylactic reactions to neuromuscular blocking agents: can they be prevented? 30 Aug 2008
• Evaluation of anti-tussive activity of Chamaedorea tepejilote. 6 Aug 2008
• Design and synthesis of a metabolically stable and potent antitussive agent, a novel delta opioid receptor antagonist, TRK-851. 27 Jul 2008
• [Multimodal treatment of pain and nausea in breast cancer surgery] 31 May 2008
• [Postoperative inconveniences after breast cancer surgery] 31 May 2008
• Codeine induced respiratory depression in a child. 28 Feb 2008
• Over-the-counter medications for acute cough in children and adults in ambulatory settings. 21 Jan 2008

See a longer list of these articles.

Technical information about 'Antitussive Agents'

Definition: Agents that suppress cough. They act centrally on the medullary cough center. EXPECTORANTS, also used in the treatment of cough, act locally.

Registry Number: 0

Descriptor UI: D000996

Alternative terms: Antitussive Agents; Agents, Antitussive; Antitussive Drugs; Drugs, Antitussive; Antitussives;

Related Mesh Headings: Expectorants;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D27.505.954.427.153; D27.505.954.796.090;

Technical Notes: GEN or unspecified; consider also COUGH /drug ther