Aphasia, Primary Progressive - Research News and Information

Thursday, January 08, 2009

Cognitive deficits and reduced insight in primary progressive aphasia.

30 Jul 2008 Primary progressive aphasia (PPA) is a form of dementia caused by frontotemporal lobar degeneration. Unlike aphasia due to stroke, in which the association between particular aphasia profiles and insight has been well characterized, this ... Read more...

The logopenic/phonological variant of primary progressive aphasia.

14 Jul 2008 OBJECTIVE: Primary progressive aphasia (PPA) is characterized by isolated decline in language functions. Semantic dementia and progressive nonfluent aphasia are accepted PPA variants. A "logopenic" variant (LPA) has also been proposed, but its ... Read more...

Language performance in Alzheimer's disease and mild cognitive impairment: a comparative review.

29 Jun 2008 Mild cognitive impairment (MCI) manifests as memory impairment in the absence of dementia and progresses to Alzheimer's disease (AD) at a rate of around 15% per annum, versus 1-2% in the general population. It thus constitutes a primary target for ... Read more...

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Latest indexed articles for 'Aphasia, Primary Progressive'

These are the very latest articles for this heading:

• Lost for words. Sep 2008
• Cognitive deficits and reduced insight in primary progressive aphasia. 30 Jul 2008
• Corticobasal syndrome and primary progressive aphasia as manifestations of lrrk2 gene mutations. 20 Jul 2008
• The logopenic/phonological variant of primary progressive aphasia. 14 Jul 2008
• Primary progressive aphasia: quantitative analysis. 6 Jul 2008
• Paroxysmal movement disorders in GLUT1 deficiency syndrome. 6 Jul 2008
• Language performance in Alzheimer's disease and mild cognitive impairment: a comparative review. 29 Jun 2008
• "Much Madness is Divinest Sense". 29 Jun 2008
• [Amusia and aphasia of Bolero's creator--influence of the right hemisphere on music] 29 Jun 2008
• Alzheimer and frontotemporal pathology in subsets of primary progressive aphasia. 30 May 2008
• Patient care and management of frontotemporal lobar degeneration. 30 Mar 2008
• Clinicopathological and genetic correlates of frontotemporal lobar degeneration and corticobasal degeneration. 23 Mar 2008
• J. Clifford Richardson and 50 years of progressive supranuclear palsy. 10 Feb 2008
• Phenotype variability in progranulin mutation carriers: a clinical, neuropsychological, imaging and genetic study. 30 Jan 2008
• Increased frequency of learning disability in patients with primary progressive aphasia and their first-degree relatives. 30 Jan 2008
• [Primary progressive aphasia: a specific consideration among the neurodegenerative pathology] 23 Jan 2008
• Self-awareness and self-monitoring of cognitive and behavioral deficits in behavioral variant frontotemporal dementia, primary progressive aphasia and probable Alzheimer's disease. 12 Jan 2008
• Galantamine in frontotemporal dementia and primary progressive aphasia. 12 Jan 2008
• Correlative studies of structural and functional imaging in primary progressive aphasia. 9 Jan 2008
• Primary progressive aphasia pathology. 30 Dec 2007

See a longer list of these articles.

Technical information about 'Aphasia, Primary Progressive'

Definition: A progressive form of dementia characterized by the global loss of language abilities and initial preservation of other cognitive functions. Fluent and nonfluent subtypes have been described. Eventually a pattern of global cognitive dysfunction, similar to ALZHEIMER DISEASE, emerges. Pathologically, there are no Alzheimer or PICK DISEASE like changes, however, spongiform changes of cortical layers II and III are present in the TEMPORAL LOBE and FRONTAL LOBE. (From Brain 1998 Jan;121(Pt 1):115-26)

Descriptor UI: D018888

Alternative terms: Aphasia, Primary Progressive; Aphasias, Primary Progressive; Primary Progressive Aphasia; Primary Progressive Aphasias; Progressive Aphasia, Primary; Progressive Aphasias, Primary; Mesulam's Syndrome; Syndrome, Mesulam's; Mesulam Syndrome; Syndrome, Mesulam; Progressive Nonfluent Aphasia; Aphasia, Progressive Nonfluent; Aphasias, Progressive Nonfluent; Nonfluent Aphasia, Progressive; Nonfluent Aphasias, Progressive; Progressive Nonfluent Aphasias;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; diagnosis; diet therapy; drug therapy; economics; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; rehabilitation; surgery; therapy; urine; ultrasonography; virology;

Tree Number: C10.228.140.380.132; C10.597.606.150.500.800.100.155; C23.888.592.604.150.500.800.100.155; F03.087.400.125;

History Note: 1996

Technical Notes: a clin entity: do not confuse with descriptions of the progression of aphasia in case reports