Aplysia
Research News and Information

Monday, November 23, 2009

Main immunogenic region structure promotes binding of conformation-dependent myasthenia gravis autoantibodies, nicotinic acetylcholine receptor conformation maturation, and agonist sensitivity.

2 Nov 2009 The main immunogenic region (MIR) is a conformation-dependent region at the extracellular apex of alpha1 subunits of muscle nicotinic acetylcholine receptor (AChR) that is the target of half or more of the autoantibodies to muscle AChRs in human ... Read more...

Characterization of small RNAs in aplysia reveals a role for miR-124 in constraining synaptic plasticity through CREB.

22 Sep 2009 Memory storage and memory-related synaptic plasticity rely on precise spatiotemporal regulation of gene expression. To explore the role of small regulatory RNAs in learning-related synaptic plasticity, we carried out massive parallel sequencing to ... Read more...

MicroRNAs in memory processing.

22 Sep 2009 MicroRNAs are a class of small RNA molecules that regulate the expression of a wide variety of genes. In this issue of Neuron, Rajasethupathy and colleagues identify 170 distinct microRNAs in Aplysia, including one, miR-124, that plays a critical ... Read more...

Latest indexed articles for 'Aplysia'

These are the very latest articles for this heading:

• Main immunogenic region structure promotes binding of conformation-dependent myasthenia gravis autoantibodies, nicotinic acetylcholine receptor conformation maturation, and agonist sensitivity. 2 Nov 2009
• Characterization of small RNAs in aplysia reveals a role for miR-124 in constraining synaptic plasticity through CREB. 22 Sep 2009
• MicroRNAs in memory processing. 22 Sep 2009
• Transcriptome analysis of the central nervous system of the mollusc Lymnaea stagnalis. 21 Sep 2009
• Distinct inhibitory neurons exert temporally specific control over activity of a motoneuron receiving concurrent excitation and inhibition. 21 Sep 2009
• Metabolites from the sea hare Aplysia fasciata. 30 Aug 2009
• Interaction of alpha-conotoxin ImII and its analogs with nicotinic receptors and acetylcholine-binding proteins: additional binding sites on Torpedo receptor. 25 Aug 2009
• Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal alpha7 nicotinic acetylcholine receptor. 18 Aug 2009
• PKC differentially translocates during spaced and massed training in Aplysia. 17 Aug 2009
• Identification of a serotonin receptor coupled to adenylyl cyclase involved in learning-related heterosynaptic facilitation in Aplysia. 9 Aug 2009
• Detecting intrinsic scattering changes correlated to neuron action potentials using optical coherence imaging. Aug 2009
• Poly-(ADP-ribose) polymerase-1 is necessary for long-term facilitation in Aplysia. 27 Jul 2009
• Structural basis for enzymatic evolution from a dedicated ADP-ribosyl cyclase to a multifunctional NAD hydrolase. 26 Jul 2009
• Two distinct mechanisms mediate potentiating effects of depolarization on synaptic transmission. 13 Jul 2009
• Capillary electrophoresis with electrospray ionization mass spectrometric detection for single-cell metabolomics. 13 Jul 2009
• Learning and memory: how sea slug behaviors become compulsive. 12 Jul 2009
• Purification and biochemical characterization of a D-galactose binding lectin from Japanese sea hare (Aplysia kurodai) eggs. 29 Jun 2009
• Molecular identification of candidate chemoreceptor genes and signal transduction components in the sensory epithelium of Aplysia. 29 Jun 2009
• Collecting peptide release from the brain using porous polymer monolith-based solid phase extraction capillaries. 29 Jun 2009
• Aplysia cys-loop glutamate-gated chloride channels reveal convergent evolution of ligand specificity. 23 Jun 2009

See a longer list of these articles.

Technical information about 'Aplysia'

Definition: An opisthobranch mollusk of the order Anaspidea. It is used frequently in studies of nervous system development because of its large identifiable neurons. Aplysiatoxin and its derivatives are not biosynthesized by Aplysia, but acquired by ingestion of Lyngbya (seaweed) species.

Descriptor UI: D001048

Alternative terms: Aplysia;

Allowable Qualifiers: anatomy & histology; classification; cytology; drug effects; embryology; enzymology; genetics; growth & development; immunology; metabolism; microbiology; parasitology; pathogenicity; physiology; radiation effects; ultrastructure; chemistry; virology;

Tree Number: B01.500.644.400.060;

History Note: 78

Technical Notes: mollusk; /microbiol /parasitol /virol permitted