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Aptamers, Nucleotide - Chemistry
Research News and Information
Definition of 'Aptamers, Nucleotide'Nucleotide sequences, generated by iterative rounds of SELEX APTAMER TECHNIQUE, that bind to a target molecule specifically and with high affinity. Common names: Aptamers, Nucleotide; Nucleotide Aptamers; RNA Aptamers; Aptamers, RNA; Oligonucleotide Ligands, RNA; RNA Oligonucleotide Ligands; DNA Aptamers; Aptamers, DNA; Oligonucleotide Ligands, DNA; DNA Oligonucleotide Ligands |
Sunday, November 22, 2009
A variant riboswitch aptamer class for S-adenosylmethionine common in marine bacteria.
21 Sep 2009 
Riboswitches that sense S-adenosylmethionine (SAM) are widely distributed throughout a variety of bacterial lineages. Four classes of SAM-binding riboswitches have been reported to date, constituting the most diverse collection of riboswitch classes ... Read more...
Preliminary development of DNA aptamer-Fc conjugate opsonins.
13 Sep 2009 Encapsulated bacteria such as virulent strains of Bacillus anthracis impair phagocytosis with their capsules unless opsonized by antibodies. Poly-gamma-D-glutamic acid (gamma-PDGA) is the major component of the B. anthracis capsule. In this work, ... Read more...
Noncompetitive fluorescence polarization aptamer-based assay for small molecule detection.
30 Aug 2009 In this paper, a new fluorescence polarization (FP) assay strategy is described reporting the first demonstration of a noncompetitive FP technique dedicated to the small molecule sensing. This approach was based on the unique induced-fit binding ... Read more...
Latest indexed articles for 'Aptamers, Nucleotide - Chemistry'
These are the very latest articles for this heading:
- A variant riboswitch aptamer class for S-adenosylmethionine common in marine bacteria. 21 Sep 2009
- Preliminary development of DNA aptamer-Fc conjugate opsonins. 13 Sep 2009
- Noncompetitive fluorescence polarization aptamer-based assay for small molecule detection. 30 Aug 2009
- Sensitive and visual detection of adenosine by a rationally designed FokI-based biosensing strategy.
30 Aug 2009 - An electrochemiluminescent aptamer switch for a high-throughput assay of an RNA editing reaction. 18 Aug 2009
- Retention of function in the DNA homolog of the RNA dopamine aptamer. 18 Aug 2009
- Viral capsid DNA aptamer conjugates as multivalent cell-targeting vehicles. 10 Aug 2009
- Treating age-related macular degeneration - interaction of VEGF-antagonists with their target. 30 Jul 2009
- Colorimetric split G-quadruplex probes for nucleic acid sensing: improving reconstituted DNAzyme's catalytic efficiency via probe remodeling. 27 Jul 2009
- Single-molecule imaging of an in vitro-evolved RNA aptamer reveals homogeneous ligand binding kinetics.
27 Jul 2009 - MD simulations of ligand-bound and ligand-free aptamer: molecular level insights into the binding and switching mechanism of the add A-riboswitch. 20 Jul 2009
- Aptamers and aptamer targeted delivery. 16 Jul 2009
- A novel near-infrared protein assay based on the dissolution and aggregation of aptamer-wrapped single-walled carbon nanotubes. 12 Jul 2009
- Aptamer-based regionally protected PCR for protein detection. 7 Jul 2009
- Easy design of logic gates based on aptazymes and noncrosslinking gold nanoparticle aggregation. 5 Jul 2009
- Cell-free cloning using multiply-primed rolling circle amplification with modified RNA primers. 29 Jun 2009
- Peptide- and aptamer-functionalized nanovectors for targeted delivery of therapeutics. 29 Jun 2009
- Resonance scattering spectral detection of trace Hg2+ using aptamer-modified nanogold as probe and nanocatalyst. 29 Jun 2009
- Generation of highly specific aptamers via micromagnetic selection. 29 Jun 2009
- Label-free electrochemical detection of adenosine based on electron transfer from guanine bases in an adenosine-sensitive aptamer. 28 Jun 2009
See a longer list of these articles.
Technical information about 'Aptamers, Nucleotide'
Definition: Nucleotide sequences, generated by iterative rounds of SELEX APTAMER TECHNIQUE, that bind to a target molecule specifically and with high affinity.
Registry Number: 0
Descriptor UI: D052157
Alternative terms: Aptamers, Nucleotide; Nucleotide Aptamers; RNA Aptamers; Aptamers, RNA; Oligonucleotide Ligands, RNA; RNA Oligonucleotide Ligands; DNA Aptamers; Aptamers, DNA; Oligonucleotide Ligands, DNA; DNA Oligonucleotide Ligands;
Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;
Tree Number: D13.695.578.424.224;
History Note: 2006