Aptamers, Nucleotide - Metabolism
Research News and Information

Monday, November 23, 2009

A variant riboswitch aptamer class for S-adenosylmethionine common in marine bacteria.

21 Sep 2009 Riboswitches that sense S-adenosylmethionine (SAM) are widely distributed throughout a variety of bacterial lineages. Four classes of SAM-binding riboswitches have been reported to date, constituting the most diverse collection of riboswitch classes ... Read more...

Recognition imaging of acetylated chromatin using a DNA aptamer.

14 Sep 2009 Histone acetylation plays an important role in the regulation of gene expression. A DNA aptamer generated by in vitro selection to be highly specific for histone H4 protein acetylated at lysine 16 was used as a recognition element for atomic force ... Read more...

Aptamer-based microfluidic device for enrichment, sorting, and detection of multiple cancer cells.

30 Aug 2009 The ability to diagnose cancer based on the detection of rare cancer cells in blood or other bodily fluids is a significant challenge. To address this challenge, we have developed a microfluidic device that can simultaneously sort, enrich, and then ... Read more...

Latest indexed articles for 'Aptamers, Nucleotide - Metabolism'

These are the very latest articles for this heading:

• A variant riboswitch aptamer class for S-adenosylmethionine common in marine bacteria. 21 Sep 2009
• Recognition imaging of acetylated chromatin using a DNA aptamer. 14 Sep 2009
• Aptamer-based microfluidic device for enrichment, sorting, and detection of multiple cancer cells. 30 Aug 2009
• Aptamer-linked assay for thrombin using gold nanoparticle amplification and inductively coupled plasma-mass spectrometry detection. 30 Aug 2009
• Noncompetitive fluorescence polarization aptamer-based assay for small molecule detection. 30 Aug 2009
• Kinetic optimization of a protein-responsive aptamer beacon. 13 Aug 2009
• Inhibiting Plasmodium falciparum growth and heme detoxification pathway using heme-binding DNA aptamers. 22 Jul 2009
• MD simulations of ligand-bound and ligand-free aptamer: molecular level insights into the binding and switching mechanism of the add A-riboswitch. 20 Jul 2009
• Aptamers and aptamer targeted delivery. 16 Jul 2009
• In vivo tissue engineering of heart valves: evolution of a novel concept. 29 Jun 2009
• A mathematical feasibility argument for the use of aptamers in chemotherapy and imaging. 16 Jun 2009
• Unbiased RNA-protein interaction screen by quantitative proteomics. 14 Jun 2009
• Simultaneously fluorescence detecting thrombin and lysozyme based on magnetic nanoparticle condensation. 25 May 2009
• Histone H3 N-terminal peptide binds directly to its own mRNA: a possible mode of feedback inhibition to control translation. 23 May 2009
• The fabrication, characterization and application of aptamer-functionalized Si-nanowire FET biosensors. 16 May 2009
• Locked nucleic acid nucleoside triphosphates and polymerases: on the way towards evolution of LNA aptamers. 13 May 2009
• Evolution of a histone H4-K16 acetyl-specific DNA aptamer. 11 May 2009
• Fluorophore binding aptamers as a tool for RNA visualization. 4 May 2009
• Evidence for pseudoknot formation of class I preQ1 riboswitch aptamers. 2 May 2009
• Combinatorial synthesis of thrombin-binding aptamers containing iso-guanine. 29 Apr 2009

See a longer list of these articles.

Technical information about 'Aptamers, Nucleotide'

Definition: Nucleotide sequences, generated by iterative rounds of SELEX APTAMER TECHNIQUE, that bind to a target molecule specifically and with high affinity.

Registry Number: 0

Descriptor UI: D052157

Alternative terms: Aptamers, Nucleotide; Nucleotide Aptamers; RNA Aptamers; Aptamers, RNA; Oligonucleotide Ligands, RNA; RNA Oligonucleotide Ligands; DNA Aptamers; Aptamers, DNA; Oligonucleotide Ligands, DNA; DNA Oligonucleotide Ligands;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D13.695.578.424.224;

History Note: 2006