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Aptamers, Nucleotide
Research News and Information
Definition of 'Aptamers, Nucleotide'Nucleotide sequences, generated by iterative rounds of SELEX APTAMER TECHNIQUE, that bind to a target molecule specifically and with high affinity. Common names: Aptamers, Nucleotide; Nucleotide Aptamers; RNA Aptamers; Aptamers, RNA; Oligonucleotide Ligands, RNA; RNA Oligonucleotide Ligands; DNA Aptamers; Aptamers, DNA; Oligonucleotide Ligands, DNA; DNA Oligonucleotide Ligands |
Sunday, November 22, 2009
Development of universal antidotes to control aptamer activity.
2 Oct 2009 
With an ever increasing number of people taking numerous medications, the need to safely administer drugs and limit unintended side effects has never been greater. Antidote control remains the most direct means to counteract acute side effects of ... Read more...
29 Sep 2009 Inhibition of angiogenesis is critical in the prevention and treatment of neovascular age-related macular degeneration (AMD). Pathologic states such as hypoxia, ischemia, or inflammation may tip the balance of proangiogenic and antiangiogenic ... Read more...
A variant riboswitch aptamer class for S-adenosylmethionine common in marine bacteria.
21 Sep 2009 Riboswitches that sense S-adenosylmethionine (SAM) are widely distributed throughout a variety of bacterial lineages. Four classes of SAM-binding riboswitches have been reported to date, constituting the most diverse collection of riboswitch classes ... Read more...
Latest indexed articles for 'Aptamers, Nucleotide'
These are the very latest articles for this heading:
- Rapid and persistent regression of severe new vessels on the disc in proliferative diabetic retinopathy after a single intravitreal injection of pegaptanib.
16 Nov 2009 - Development of universal antidotes to control aptamer activity. 2 Oct 2009
- Introduction: Understanding the role of angiogenesis and antiangiogenic agents in age-related macular degeneration. 29 Sep 2009
- A variant riboswitch aptamer class for S-adenosylmethionine common in marine bacteria. 21 Sep 2009
- Recognition imaging of acetylated chromatin using a DNA aptamer. 14 Sep 2009
- Preliminary development of DNA aptamer-Fc conjugate opsonins. 13 Sep 2009
- Aptamer-based microfluidic device for enrichment, sorting, and detection of multiple cancer cells. 30 Aug 2009
- Aptamer-linked assay for thrombin using gold nanoparticle amplification and inductively coupled plasma-mass spectrometry detection. 30 Aug 2009
- Noncompetitive fluorescence polarization aptamer-based assay for small molecule detection. 30 Aug 2009
- Sensitive and visual detection of adenosine by a rationally designed FokI-based biosensing strategy. 30 Aug 2009
- Foveal geographic atrophy following intravitreal pegaptanib sodium (Macugen) for drusenoid pigment epithelium detachment. 30 Aug 2009
- Antidote-controlled antithrombotic therapy targeting factor IXa and von Willebrand factor. 30 Aug 2009
- Disease-specific biomarker discovery by aptamers. 30 Aug 2009
- Safety implications of vascular endothelial growth factor blockade for subjects receiving intravitreal anti-vascular endothelial growth factor therapies. 24 Aug 2009
- An electrochemiluminescent aptamer switch for a high-throughput assay of an RNA editing reaction. 18 Aug 2009
- Retention of function in the DNA homolog of the RNA dopamine aptamer. 18 Aug 2009
- Kinetic optimization of a protein-responsive aptamer beacon. 13 Aug 2009
- Intravitreal pegaptanib sodium (Macugen) for diabetic macular oedema. 10 Aug 2009
- Viral capsid DNA aptamer conjugates as multivalent cell-targeting vehicles. 10 Aug 2009
- Aptamers as inhibitors of target proteins. 30 Jul 2009
See a longer list of these articles.
Technical information about 'Aptamers, Nucleotide'
Definition: Nucleotide sequences, generated by iterative rounds of SELEX APTAMER TECHNIQUE, that bind to a target molecule specifically and with high affinity.
Registry Number: 0
Descriptor UI: D052157
Alternative terms: Aptamers, Nucleotide; Nucleotide Aptamers; RNA Aptamers; Aptamers, RNA; Oligonucleotide Ligands, RNA; RNA Oligonucleotide Ligands; DNA Aptamers; Aptamers, DNA; Oligonucleotide Ligands, DNA; DNA Oligonucleotide Ligands;
Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;
Tree Number: D13.695.578.424.224;
History Note: 2006