Aromatase Inhibitors
Research News and Information

Sunday, November 22, 2009

Chronic exposure to anabolic androgenic steroids alters neuronal function in the mammalian forebrain via androgen receptor- and estrogen receptor-mediated mechanisms.

5 Oct 2009 Anabolic androgenic steroids (AAS) can promote detrimental effects on social behaviors for which GABA type A (GABA(A)) receptor-mediated circuits in the forebrain play a critical role. While all AAS bind to androgen receptors (AR), they may also be ... Read more...

Nuclear receptor co-activators and HER-2/neu are upregulated in breast cancer patients during neo-adjuvant treatment with aromatase inhibitors.

13 Sep 2009 BACKGROUND: Acquired resistance to endocrine therapy in breast cancer is poorly understood. Characterisation of the molecular response to aromatase inhibitors in breast cancer tissue may provide important information regarding development of ... Read more...

Strategies for maximizing growth in puberty in children with short stature.

30 Aug 2009 The approach to the child with growth retardation who is in puberty remains an important clinical challenge. The use of high-dose growth hormone (GH), suppression of puberty with GnRH analogs in combination with GH, and the use of selective ... Read more...

Latest indexed articles for 'Aromatase Inhibitors'

These are the very latest articles for this heading:

• Chronic exposure to anabolic androgenic steroids alters neuronal function in the mammalian forebrain via androgen receptor- and estrogen receptor-mediated mechanisms. 5 Oct 2009
• Tamoxifen, antidepressants, and CYP2D6: the conundrum continues. 29 Sep 2009
• American Society of Clinical Oncology clinical practice guideline update on the use of pharmacologic interventions including tamoxifen, raloxifene, and aromatase inhibition for breast cancer risk reduction. 29 Sep 2009
• Nuclear receptor co-activators and HER-2/neu are upregulated in breast cancer patients during neo-adjuvant treatment with aromatase inhibitors. 13 Sep 2009
• Strategies for maximizing growth in puberty in children with short stature. 30 Aug 2009
• [Efficacy and safety of high-dose toremifene for hormone-responsive advanced or metastatic breast cancer patients with failed prior treatment by aromatase inhibitors] 30 Aug 2009
• Involvement of resistance to apoptosis in the pathogenesis of endometriosis. 30 Aug 2009
• Long-term potentiation in the rat medial vestibular nuclei depends on locally synthesized 17beta-estradiol. 24 Aug 2009
• Letrozole therapy alone or in sequence with tamoxifen in women with breast cancer. 18 Aug 2009
• Estradiol in breast cancer treatment: reviving the past. 17 Aug 2009
• Lower-dose vs high-dose oral estradiol therapy of hormone receptor-positive, aromatase inhibitor-resistant advanced breast cancer: a phase 2 randomized study. 17 Aug 2009
• Patterns and risk factors associated with aromatase inhibitor-related arthralgia among breast cancer survivors. 13 Aug 2009
• Tamoxifen: the drug that came in from the cold. 9 Aug 2009
• Visual impairment in myopic patients with breast cancer receiving adjuvant therapy with aromatase inhibitors. 30 Jul 2009
• Cholesterol-promoted synaptogenesis requires the conversion of cholesterol to estradiol in the hippocampus. 30 Jul 2009
• Effect of aromatase inhibitors on lipid metabolism, inflammatory response and antioxidant balance in patients with breast carcinoma. 30 Jul 2009
• Adjuvant endocrine therapy in post menopausal women: pharmacological evaluation using decision analysis approach in a Japanese hospital setting. 30 Jul 2009
• Altered gene expression in the brain and ovaries of zebrafish (Danio rerio) exposed to the aromatase inhibitor fadrozole: microarray analysis and hypothesis generation. 30 Jul 2009
• Aromatase inhibitor for treatment of a recurrent abdominal wall endometrioma in a postmenopausal woman. 7 Jul 2009
• Aromatase inhibitors for ovulation and pregnancy in polycystic ovary syndrome. 5 Jul 2009

See a longer list of these articles.

Technical information about 'Aromatase Inhibitors'

Definition: Compounds that inhibit AROMATASE in order to reduce production of estrogenic steroid hormones.

Registry Number: 0

Descriptor UI: D047072

Alternative terms: Aromatase Inhibitors; Inhibitors, Aromatase;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D27.505.519.389.099;

History Note: 2005