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Arrestins - Genetics
Research News and Information
Definition of 'Arrestins'Regulatory proteins that down-regulate phosphorylated G-protein membrane receptors, including rod and cone photoreceptors and adrenergic receptors. Common names: Arrestins |
Sunday, November 22, 2009
Arrestin2/clathrin interaction is regulated by key N- and C-terminal regions in arrestin2.
2 Aug 2009 
The interaction of nonvisual arrestins with clathrin is an important step in mediating the endocytosis of cell surface receptors. Previous studies have shown that mutation of the clathrin-binding box in arrestin leads to severe defects in ... Read more...
7 Jun 2009 beta1-Adrenergic receptor (beta1AR) stimulation confers cardioprotection via beta-arrestin-de pend ent transactivation of epidermal growth factor receptors (EGFRs), however, the precise mechanism for this salutary process is unknown. We tested the ... Read more...
30 May 2009 Nicotine sensitization and levels of brain-derived neurotrophic factor (BDNF) were analyzed in adolescent beta-arrestin-2 knockout (betaA-2 KO) and wild type (WT) mice. The beta-arrestin-2 protein has been shown to be important in G-protein ... Read more...
Latest indexed articles for 'Arrestins - Genetics'
These are the very latest articles for this heading:
- Arrestin2/clathrin interaction is regulated by key N- and C-terminal regions in arrestin2. 2 Aug 2009
- beta-Arrestin mediates beta1-adrenergic receptor-epidermal growth factor receptor interaction and downstream signaling. 7 Jun 2009
- Nicotine sensitization and analysis of brain-derived neurotrophic factor in adolescent beta-arrestin-2 knockout mice. 30 May 2009
- Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression. 26 May 2009
- HIV-1 gp120 primes lymphocytes for opioid-induced, beta-arrestin 2-dependent apoptosis. 25 May 2009
- Beta-arrestin 2 is required for the induction and strengthening of integrin-mediated leukocyte adhesion during CXCR2-driven extravasation. 6 May 2009
- Paracrine transactivation of the CB1 cannabinoid receptor by AT1 angiotensin and other Gq/11 protein-coupled receptors. 5 Apr 2009
- beta-Arrestin1 mediates nicotinic acid-induced flushing, but not its antilipolytic effect, in mice.
4 Apr 2009 - G protein independent phosphorylation and internalization of the delta-opioid receptor. 30 Mar 2009
- The type III transforming growth factor-beta receptor negatively regulates nuclear factor kappa B signaling through its interaction with beta-arrestin2. 24 Mar 2009
- Prolonged RXFP1 and RXFP2 signaling can be explained by poor internalization and a lack of beta-arrestin recruitment. 9 Mar 2009
- Two distinct mechanisms mediate acute mu-opioid receptor desensitization in native neurons. 9 Mar 2009
- Independent beta-arrestin2 and Gq/protein kinase Czeta pathways for ERK stimulated by angiotensin type 1A receptors in vascular smooth muscle cells converge on transactivation of the epidermal growth factor receptor. 28 Feb 2009
- Insulin action under arrestin. 27 Feb 2009
- Deficiency of a beta-arrestin-2 signal complex contributes to insulin resistance. 24 Feb 2009
- Agonist-independent interactions between beta-arrestins and mutant vasopressin type II receptors associated with nephrogenic syndrome of inappropriate antidiuresis. 27 Jan 2009
- The 27-kDa heat shock protein confers cytoprotective effects through a beta 2-adrenergic receptor agonist-initiated complex with beta-arrestin. 25 Jan 2009
- {beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation. 24 Jan 2009
- Beta2-adrenergic receptor regulate Toll-like receptor 4-induced late-phase NF-kappaB activation. 20 Jan 2009
- Obestatin stimulates Akt signalling in gastric cancer cells through beta-arrestin-mediated epidermal growth factor receptor transactivation. 17 Jan 2009
See a longer list of these articles.
Technical information about 'Arrestins'
Definition: Regulatory proteins that down-regulate phosphorylated G-protein membrane receptors, including rod and cone photoreceptors and adrenergic receptors.
Registry Number: 0
Descriptor UI: D019390
Alternative terms: Arrestins;
Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;
Tree Number: D12.776.306.090; D12.776.543.090;
History Note: 97
Technical Notes: regulatory proteins; do not confuse with ARRESTIN