Ascorbic Acid
Research News and Information

Monday, November 23, 2009

Importance of the conserved lysine 83 residue of Zea mays cytochrome b(561) for ascorbate-specific transmembrane electron transfer as revealed by site-directed mutagenesis studies.

8 Nov 2009 Cytochromes b(561), a novel class of transmembrane electron transport proteins residing in a large variety of eukaryotic cells, have a number of common structural features including six hydrophobic transmembrane alpha-helices and two heme ligation ... Read more...

Cytocompatibility studies of an in situ photopolymerized thermoresponsive hydrogel nanoparticle system using human aortic smooth muscle cells.

29 Sep 2009 We have been investigating thermoresponsive hydrogel nanoparticle composite networks to develop photopolymerized hydrogels to deliver drugs for prevention of restenosis after angioplasty. These composite systems can form a gel under physiological ... Read more...

Antioxidants and aging: NMR-based evidence of improved skeletal muscle perfusion and energetics.

16 Sep 2009 We sought to examine the potential role of oxidative stress on skeletal muscle function with advancing age. Nuclear magnetic resonance (NMR) was employed to simultaneously assess muscle perfusion (arterial spin labeling) and energetics ((31)P NMR ... Read more...

Latest indexed articles for 'Ascorbic Acid'

These are the very latest articles for this heading:

• Importance of the conserved lysine 83 residue of Zea mays cytochrome b(561) for ascorbate-specific transmembrane electron transfer as revealed by site-directed mutagenesis studies. 8 Nov 2009
• Quality of life in children with CMT type 1A. 29 Sep 2009
• Cytocompatibility studies of an in situ photopolymerized thermoresponsive hydrogel nanoparticle system using human aortic smooth muscle cells. 29 Sep 2009
• Antioxidants and aging: NMR-based evidence of improved skeletal muscle perfusion and energetics. 16 Sep 2009
• Unrecognised scurvy. 15 Sep 2009
• Hepatocyte nuclear factor 1 is essential for transcription of sodium-dependent vitamin C transporter protein 1. 7 Sep 2009
• Mechanism of action of novel naphthofuranquinones on rat liver microsomal peroxidation. 6 Sep 2009
• Hepatoprotection of chlorella against carbon tetrachloride-induced oxidative damage in rats. 30 Aug 2009
• High baseline vitamin C levels do not prevent a positive outcome of a lifestyle intervention. 30 Aug 2009
• Half-life mapping of nitroxyl radicals with three-dimensional electron paramagnetic resonance imaging at an interval of 3.6 seconds. 30 Aug 2009
• Genotoxic effects of carotenoid breakdown products in human retinal pigment epithelial cells. 30 Aug 2009
• Maternal alcohol consumption may influence cord blood ascorbic acid concentration: findings from a study of Brazilian mothers and their newborns. 30 Aug 2009
• Changes in antioxidant status and lipid peroxidation in Nigerian patients with prostate carcinoma. 30 Aug 2009
• Plasma vitamin C is lower in postherpetic neuralgia patients and administration of vitamin C reduces spontaneous pain but not brush-evoked pain. 30 Aug 2009
• Lyophilized plasma for resuscitation in a swine model of severe injury. 30 Aug 2009
• Vitamins C and E for the prevention of pre-eclampsia: time to give up the ghost*. 30 Aug 2009
• Beta-catenin regulates vitamin C biosynthesis and cell survival in murine liver. 16 Aug 2009
• Artefacts in cell culture: pyruvate as a scavenger of hydrogen peroxide generated by ascorbate or epigallocatechin gallate in cell culture media. 16 Aug 2009
• Generation of oxidant response to copper and iron nanoparticles and salts: Stimulation by ascorbate. 12 Aug 2009
• Development of a high methoxyl pectin edible film for retention of l-(+)-ascorbic acid. 10 Aug 2009

See a longer list of these articles.

Technical information about 'Ascorbic Acid'

Definition: A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.

Chemical name: L-Ascorbic acid

Registry Number: 50-81-7

Descriptor UI: D001205

Alternative terms: Ascorbic Acid; Acid, Ascorbic; Vitamin C; L-Ascorbic Acid; Acid, L-Ascorbic; L Ascorbic Acid; Sodium Ascorbate; Ascorbate, Sodium; Ascorbic Acid, Monosodium Salt; Magnesium Ascorbicum; Magnorbin; Ferrous Ascorbate; Ascorbate, Ferrous; Hybrin;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Antioxidants; Vitamins;

Tree Number: D02.241.081.844.107; D02.241.511.902.107; D09.811.100;

History Note: /therapeutic use was ASCORBIC ACID, THERAPEUTIC 1965

Technical Notes: /defic = ASCORBIC ACID DEFICIENCY or SCURVY