Aspirin - Adverse effects
Research News and Information

Monday, November 23, 2009

Aspirin for primary prevention of cardiovascular events in people with diabetes: meta-analysis of randomised controlled trials.

4 Nov 2009 OBJECTIVE: To evaluate the benefits and harms of low dose aspirin in people with diabetes and no cardiovascular disease. DESIGN: Meta-analysis of randomised controlled trials. DATA SOURCES: Medline (1966-November 2008), the Cochrane central register ... Read more...

Genetic effect of CysLTR2 polymorphisms on its mRNA synthesis and stabilization.

18 Oct 2009 BACKGROUND: We previously demonstrated that single nucleotide polymorphism (SNP) and haplotypes were associated with aspirin hypersensitivity in asthmatics. We investigated the genetic effects of the SNPs and haplotypes on the expression of the ... Read more...

Bleeding increases the risk of ischemic events in patients with peripheral arterial disease.

3 Oct 2009 BACKGROUND: Patients with peripheral arterial disease are at high risk of ischemic events and therefore are treated with antithrombotics. In patients with coronary artery disease or cerebrovascular disease, bleeding is related to the subsequent ... Read more...

Latest indexed articles for 'Aspirin - Adverse effects'

These are the very latest articles for this heading:

• Aspirin for primary prevention of vascular disease in people with diabetes. 4 Nov 2009
• Aspirin for primary prevention of cardiovascular events in people with diabetes: meta-analysis of randomised controlled trials. 4 Nov 2009
• Genetic effect of CysLTR2 polymorphisms on its mRNA synthesis and stabilization. 18 Oct 2009
• Bleeding increases the risk of ischemic events in patients with peripheral arterial disease. 3 Oct 2009
• Antiplatelet agents used for early intervention in acute coronary syndrome: myocardial salvage versus bleeding complications. 29 Sep 2009
• Clopidogrel plus aspirin in atrial fibrillation. 22 Sep 2009
• Modulation by aspirin of nuclear phospho-signal transducer and activator of transcription 6 expression: Possible role in therapeutic benefit associated with aspirin desensitization. 17 Sep 2009
• Associations of functional NLRP3 polymorphisms with susceptibility to food-induced anaphylaxis and aspirin-induced asthma. 17 Sep 2009
• [Demented patient with strangulation marks. Was it a crime?] Sep 2009
• Detection of Staphylococcus aureus in nasal tissue with peptide nucleic acid-fluorescence in situ hybridization. 30 Aug 2009
• Acetylsalicylic acid use in patients with acute myocardial infarction and peptic ulcer bleeding. 30 Aug 2009
• Myocardial infarction, peptic ulcer and acetylsalicylic acid: of good and evil. 30 Aug 2009
• Perioperative anticoagulant management. 30 Aug 2009
• Comparison of bleeding complications with omega-3 fatty acids + aspirin + clopidogrel--versus--aspirin + clopidogrel in patients with cardiovascular disease. 23 Aug 2009
• Peptic ulcer disease. 11 Aug 2009
• Common drugs can harm elderly patients. 10 Aug 2009
• Unmet needs in severe chronic upper airway disease (SCUAD). 3 Aug 2009
• Rapid desensitization for hypersensitivity reactions to medications. 30 Jul 2009
• Predictive value of post-treatment platelet reactivity for occurrence of post-discharge bleeding after non-ST elevation acute coronary syndrome. Shifting from antiplatelet resistance to bleeding risk assessment? 30 Jul 2009
• Is intrinsic asthma synonymous with infection? 21 Jul 2009

See a longer list of these articles.

Technical information about 'Aspirin'

Definition: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)

Chemical name: Benzoic acid, 2-(acetyloxy)-

Registry Number: 50-78-2

Descriptor UI: D001241

Alternative terms: Aspirin; Acetylsalicylic Acid; Acid, Acetylsalicylic; 2-(Acetyloxy)benzoic Acid; Acylpyrin; Aloxiprimum; Colfarit; Dispril; Easprin; Ecotrin; Endosprin; Magnecyl; Micristin; Polopirin; Polopiryna; Solprin; Solupsan; Zorprin; Acetysal;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Anti-Inflammatory Agents, Non-Steroidal; Fibrinolytic Agents; Platelet Aggregation Inhibitors; Cyclooxygenase Inhibitors;

Tree Number: D02.241.223.100.380.800.075; D02.241.511.390.700.075; D02.755.410.700.075;

History Note: 65; was ACETYLSALICYLIC ACID 1963-64