Aspirin - Research News and Information

Thursday, January 08, 2009

Low-dose aspirin for primary prevention of atherosclerotic events in patients with type 2 diabetes: a randomized controlled trial.

7 Nov 2008 CONTEXT: Previous trials have investigated the effects of low-dose aspirin on primary prevention of cardiovascular events, but not in patients with type 2 diabetes. OBJECTIVE: To examine the efficacy of low-dose aspirin for the primary prevention ... Read more...

Cardiovascular outcomes after a change in prescription policy for clopidogrel.

21 Oct 2008 BACKGROUND: Drug-reimbursement policies may have an adverse effect on patient outcomes if they interfere with timely access to efficacious medications for acute medical conditions. Clopidogrel in combination with aspirin is the recommended standard ... Read more...

The prevention of progression of arterial disease and diabetes (POPADAD) trial: factorial randomised placebo controlled trial of aspirin and antioxidants in patients with diabetes and asymptomatic peripheral arterial disease.

14 Oct 2008 OBJECTIVE: To determine whether aspirin and antioxidant therapy, combined or alone, are more effective than placebo in reducing the development of cardiovascular events in patients with diabetes mellitus and asymptomatic peripheral arterial ... Read more...

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Latest indexed articles for 'Aspirin'

These are the very latest articles for this heading:

• Low-dose aspirin for primary prevention of atherosclerotic events in patients with type 2 diabetes: a randomized controlled trial. 7 Nov 2008
• Aspirin for primary prevention of cardiovascular events in diabetes: still an open question. 7 Nov 2008
• Cardiovascular outcomes after a change in prescription policy for clopidogrel. 21 Oct 2008
• News of the polypill. 18 Oct 2008
• Aspirin for prevention of cardiovascular events. 14 Oct 2008
• The prevention of progression of arterial disease and diabetes (POPADAD) trial: factorial randomised placebo controlled trial of aspirin and antioxidants in patients with diabetes and asymptomatic peripheral arterial disease. 14 Oct 2008
• Aspirin in type 2 diabetes: is there any evidence base? 14 Oct 2008
• The thioredoxin system mediates redox-induced cell death in human colon cancer cells: implications for the mechanism of action of anticancer agents. 13 Oct 2008
• [Thrombocyte aggregation inhibitor after surgery for an abdominal aortic aneurysm] 13 Oct 2008
• Breast cancer and use of nonsteroidal anti-inflammatory drugs: a meta-analysis. 5 Oct 2008
• [Digital ischemia in a gardener: is rose cutting a vascular risk factor?] 5 Oct 2008
• The ultimate solution to the problem of aspirin resistance. 5 Oct 2008
• Enteric coating is a possible cause of aspirin resistance. 5 Oct 2008
• Incomplete inhibition of thromboxane biosynthesis by acetylsalicylic acid: determinants and effect on cardiovascular risk. 4 Oct 2008
• Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice. 29 Sep 2008
• Pharmacokinetic and pharmacodynamic study of NO-donating aspirin in F344 rats. 29 Sep 2008
• Bleeding time prolonged by daily low-dose aspirin is shortened by one medium dose aspirin. 29 Sep 2008
• Purification, physicochemical properties, thermal analysis and antinociceptive effect of atranorin extracted from Cladina kalbii. 29 Sep 2008
• [Anticoagulation in atrial fibrillation] 29 Sep 2008
• Exodontia and antiplatelet therapy. 29 Sep 2008

See a longer list of these articles.

Technical information about 'Aspirin'

Definition: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)

Chemical name: Benzoic acid, 2-(acetyloxy)-

Registry Number: 50-78-2

Descriptor UI: D001241

Alternative terms: Aspirin; Acetylsalicylic Acid; Acid, Acetylsalicylic; 2-(Acetyloxy)benzoic Acid; Acylpyrin; Aloxiprimum; Colfarit; Dispril; Easprin; Ecotrin; Endosprin; Magnecyl; Micristin; Polopirin; Polopiryna; Solprin; Solupsan; Zorprin; Acetysal;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Anti-Inflammatory Agents, Non-Steroidal; Fibrinolytic Agents; Platelet Aggregation Inhibitors; Cyclooxygenase Inhibitors;

Tree Number: D02.241.223.100.380.800.075; D02.241.511.390.700.075; D02.755.410.700.075;

History Note: 65; was ACETYLSALICYLIC ACID 1963-64