Asthma - Drug therapy
Research News and Information

Monday, November 23, 2009

An umbrella review: corticosteroid therapy for adults with acute asthma.

30 Oct 2009 The objective of this "umbrella" review is to synthesize the evidence and provide clinicians a single report that summarizes the state of knowledge regarding the use of corticosteroids in adults with acute asthma. Systematic reviews in the Cochrane ... Read more...

5-lipoxygenase-activating protein inhibitors: development of 3-[3-tert-butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid (AM103).

6 Oct 2009 The potent and selective 5-lipoxygenase-activating protein leukotriene synthesis inhibitor 3-[3-tert-butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid (11j) is described. Lead ... Read more...

Molecular mechanisms of combination therapy with inhaled corticosteroids and long-acting beta-agonists.

29 Sep 2009 The treatment of asthma relies on the use of the following two major drug classes: beta(2)-agonists, both short acting and long acting; and corticosteroids (CSs). Although the properties of each drug class are well described, their use in ... Read more...

Latest indexed articles for 'Asthma - Drug therapy'

These are the very latest articles for this heading:

• An umbrella review: corticosteroid therapy for adults with acute asthma. 30 Oct 2009
• 5-lipoxygenase-activating protein inhibitors: development of 3-[3-tert-butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid (AM103). 6 Oct 2009
• Molecular mechanisms of combination therapy with inhaled corticosteroids and long-acting beta-agonists. 29 Sep 2009
• Asthma medication - persistence with adrenergics, steroids and combination products over a 5-year period. 29 Sep 2009
• Analysis of behavior-related adverse experiences in clinical trials of montelukast. 29 Sep 2009
• Assessing risk: Data from montelukast clinical trials. 29 Sep 2009
• Reports of suicidality in clinical trials of montelukast. 29 Sep 2009
• Sexual dimorphism: Is it relevant to steroid resistance or asthma control? 29 Sep 2009
• Vitamin D and respiratory health. 29 Sep 2009
• Cytokine and anti-cytokine therapy in asthma: ready for the clinic? 29 Sep 2009
• Vascular endothelial growth factor is a key mediator in the development of T cell priming and its polarization to type 1 and type 17 T helper cells in the airways. 26 Sep 2009
• Beliefs and barriers to follow-up after an emergency department asthma visit: a randomized trial. 26 Sep 2009
• Exhaled nitric oxide levels in asthma: Personal best versus reference values. 17 Sep 2009
• The minimally important difference of the Asthma Control Test. 17 Sep 2009
• Rethinking the pathogenesis of asthma. 16 Sep 2009
• Potential risks of using LABAs with ICS therapy. 13 Sep 2009
• Identification of an orally efficacious matrix metalloprotease 12 inhibitor for potential treatment of asthma. 8 Sep 2009
• A randomized, comparative study of formoterol and terbutaline dry powder inhalers in the treatment of mild to moderate asthma exacerbations in the pediatric acute care setting. 30 Aug 2009
• Increased oxidative stress in the airway and development of allergic inflammation in a mouse model of asthma. 30 Aug 2009
• Baseline characteristics of patients enrolled in EXCELS: a cohort study. 30 Aug 2009

See a longer list of these articles.

Technical information about 'Asthma'

Definition: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Descriptor UI: D001249

Alternative terms: Asthma; Asthmas; Asthma, Bronchial; Bronchial Asthma;

Related Mesh Headings: Anti-Asthmatic Agents;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C08.127.108; C08.381.495.108; C08.674.095; C20.543.480.680.095;

Technical Notes: ASTHMA, CARDIAC see DYSPNEA, PAROXYSMAL is available; in historical literature consider indexing "phthisic" here; "phthisis" probably goes under TUBERCULOSIS, PULMONARY