Astrocytes
Research News and Information

Saturday, November 21, 2009

Rab22B is expressed in the CNS astroglia lineage and plays a role in epidermal growth factor receptor trafficking in A431 cells.

29 Nov 2009 The expression profile and functions of the brain-enriched Rab22B/Rab31 small GTPase had remained uncharacterized. Using specific antibodies against Rab22B, we found the protein to be exceptionally enriched in nestin and RC2-positive radial glia of ... Read more...

Expression and role of CXCL10 during the encephalitic stage of experimental and clinical African trypanosomiasis.

13 Nov 2009 BACKGROUND: Human African trypanosomiasis, caused by Trypanosoma brucei, involves an early hemolymphatic stage followed by a late encephalitic stage. METHODS: We studied the expression of chemokines with use of microarray and enzyme-linked ... Read more...

Localization of zip1 and zip4 mRNA in the adult rat brain.

30 Oct 2009 The localization of two members of the Slc39a (zip1 and zip4) family of zinc transporters was examined in the brains of adult mice. Zip1 was highly enriched in brain regions with high densities of neuronal cell bodies, including the hippocampus, ... Read more...

Latest indexed articles for 'Astrocytes'

These are the very latest articles for this heading:

• Rab22B is expressed in the CNS astroglia lineage and plays a role in epidermal growth factor receptor trafficking in A431 cells. 29 Nov 2009
• Expression and role of CXCL10 during the encephalitic stage of experimental and clinical African trypanosomiasis. 13 Nov 2009
• Localization of zip1 and zip4 mRNA in the adult rat brain. 30 Oct 2009
• Extracellular matrix produced by bone marrow stromal cells and by their derivative, SB623 cells, supports neural cell growth. 30 Oct 2009
• Propofol inhibits aquaporin 4 expression through a protein kinase C-dependent pathway in an astrocyte model of cerebral ischemia/reoxygenation. 30 Oct 2009
• Astrocyte-neuron interactions: implications for epilepsy. 18 Oct 2009
• Bestrophin-1 encodes for the Ca2+-activated anion channel in hippocampal astrocytes. 12 Oct 2009
• Cognitive decline in Alzheimer's disease is associated with selective changes in calcineurin/NFAT signaling. 12 Oct 2009
• Proteomic study of neuron and astrocyte cultures from senescence-accelerated mouse SAMP8 reveals degenerative changes. 5 Oct 2009
• A PPARdelta agonist reduces amyloid burden and brain inflammation in a transgenic mouse model of Alzheimer's disease. 29 Sep 2009
• Suppression of glial HO-1 activity as a potential neurotherapeutic intervention in AD. 29 Sep 2009
• Understanding the basis for the association of apoE4 with Alzheimer's disease: opening the door for therapeutic approaches. 29 Sep 2009
• DMPK protein isoforms are differentially expressed in myogenic and neural cell lineages. 29 Sep 2009
• Astrocytes are more resistant to focal cerebral ischemia than neurons and die by a delayed necrosis. 29 Sep 2009
• Prion protein and its ligand stress inducible protein 1 regulate astrocyte development. 29 Sep 2009
• Nerve growth factor attenuates proliferation of astrocytes via the p75 neurotrophin receptor. 29 Sep 2009
• GABA uptake-dependent Ca(2+) signaling in developing olfactory bulb astrocytes. 28 Sep 2009
• Selective estrogen receptor modulators decrease reactive astrogliosis in the injured brain: effects of aging and prolonged depletion of ovarian hormones. 22 Sep 2009
• Differentiation of neurons from neural precursors generated in floating spheres from embryonic stem cells. 22 Sep 2009
• Differential SUMOylation of LXRalpha and LXRbeta mediates transrepression of STAT1 inflammatory signaling in IFN-gamma-stimulated brain astrocytes. 22 Sep 2009

See a longer list of these articles.

Technical information about 'Astrocytes'

Definition: A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from "star" cells) are irregularly shaped with many long processes, including those with "end feet" which form the glial (limiting) membrane and directly and indirectly contribute to the BLOOD-BRAIN BARRIER. They regulate the extracellular ionic and chemical environment, and "reactive astrocytes" (along with MICROGLIA) respond to injury.

Descriptor UI: D001253

Alternative terms: Astrocytes; Astrocyte; Astroglia; Astroglias;

Related Mesh Headings: Blood-Brain Barrier;

Allowable Qualifiers: classification; cytology; drug effects; enzymology; immunology; metabolism; microbiology; parasitology; pathology; physiology; radiation effects; radiography; radionuclide imaging; secretion; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A08.637.200; A11.650.200;

Online Note: search NEUROGLIA 1966-74

History Note: 79(75); was see under NEUROGLIA 1963-78