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Autistic Disorder - Genetics
Research News and Information
Definition of 'Autistic Disorder'A disorder beginning in childhood. It is marked by the presence of markedly abnormal or impaired development in social interaction and communication and a markedly restricted repertoire of activity and interest. Manifestations of the disorder vary greatly depending on the developmental level and chronological age of the individual. (DSM-IV) Common names: Autistic Disorder; Disorder, Autistic; Disorders, Autistic; Autism, Early Infantile; Early Infantile Autism; Infantile Autism, Early; Kanner's Syndrome; Kanner Syndrome; Kanners Syndrome; Syndrome, Kanner's; Autism; Autisms; Autism, Infantile; Infantile Autism |
Sunday, November 22, 2009
A genome-wide linkage and association scan reveals novel loci for autism.
6 Oct 2009 
Although autism is a highly heritable neurodevelopmental disorder, attempts to identify specific susceptibility genes have thus far met with limited success. Genome-wide association studies using half a million or more markers, particularly those ... Read more...
Characteristics and concordance of autism spectrum disorders among 277 twin pairs.
29 Sep 2009 OBJECTIVES: To examine patterns of autism spectrum disorder (ASD) inheritance and other features in twin pairs by zygosity, sex, and specific ASD diagnosis. DESIGN: Cross-sectional study. SETTING: Internet-based autism registry for US residents. ... Read more...
22 Sep 2009 BACKGROUND: Autism is a highly heritable complex neurodevelopmental disorder, therefore identifying its genetic basis has been challenging. To date, numerous susceptibility genes and chromosomal abnormalities have been reported in association with ... Read more...
Latest indexed articles for 'Autistic Disorder - Genetics'
These are the very latest articles for this heading:
- A genome-wide linkage and association scan reveals novel loci for autism. 6 Oct 2009
- Characteristics and concordance of autism spectrum disorders among 277 twin pairs. 29 Sep 2009
- Autism Genetic Database (AGD): a comprehensive database including autism susceptibility gene-CNVs integrated with known noncoding RNAs and fragile sites. 22 Sep 2009
- Journal club. A biologist praises a mouse model of autism inheritance.
22 Sep 2009 - A neuroligin-4 missense mutation associated with autism impairs neuroligin-4 folding and endoplasmic reticulum export. 31 Aug 2009
- Disparate diseases due to copycat copy number variations. 30 Aug 2009
- Clinical application of microarray-based molecular cytogenetics: an emerging new era of genomic medicine. 30 Aug 2009
- Recurrent rearrangements in synaptic and neurodevelopmental genes and shared biologic pathways in schizophrenia, autism, and mental retardation. 30 Aug 2009
- Increased brain size in autism--what it will take to solve a mystery. 13 Aug 2009
- Neurexin 1 (NRXN1) deletions in schizophrenia. 10 Aug 2009
- Aberrations in folate metabolic pathway and altered susceptibility to autism. 30 Jul 2009
- Copy number variations associated with idiopathic autism identified by whole-genome microarray-based comparative genomic hybridization. 30 Jul 2009
- Investigating epigenetic influences on seizure disposition. 30 Jul 2009
- A 1q42 deletion involving DISC1, DISC2, and TSNAX in an autism spectrum disorder. 30 Jul 2009
- Genetics and neuropsychiatric disorders: genome-wide, yet narrow. 30 Jul 2009
- SNPs in human miRNA genes affect biogenesis and function. 15 Jul 2009
- Neuroanatomic alterations and social and communication deficits in monozygotic twins discordant for autism disorder. 13 Jul 2009
- A novel missense mutation (Leu46Val) of PAX6 found in an autistic patient. 12 Jul 2009
- Allelic variants in HTR3C show association with autism. 3 Jul 2009
- Association of family history of autoimmune diseases and autism spectrum disorders. 3 Jul 2009
See a longer list of these articles.
Technical information about 'Autistic Disorder'
Definition: A disorder beginning in childhood. It is marked by the presence of markedly abnormal or impaired development in social interaction and communication and a markedly restricted repertoire of activity and interest. Manifestations of the disorder vary greatly depending on the developmental level and chronological age of the individual. (DSM-IV)
Descriptor UI: D001321
Alternative terms: Autistic Disorder; Disorder, Autistic; Disorders, Autistic; Autism, Early Infantile; Early Infantile Autism; Infantile Autism, Early; Kanner's Syndrome; Kanner Syndrome; Kanners Syndrome; Syndrome, Kanner's; Autism; Autisms; Autism, Infantile; Infantile Autism;
Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; diagnosis; diet therapy; drug therapy; economics; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; rehabilitation; surgery; therapy; urine; ultrasonography; virology;
Tree Number: F03.550.325.125;
Online Note: use AUTISM, INFANTILE to search AUTISM, EARLY INFANTILE 1971-80; use SCHIZOPHRENIA, CHILDHOOD 1968-70
History Note: 1981(1966)