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Autoimmune Diseases - Immunology
Research News and Information
Definition of 'Autoimmune Diseases'Disorders that are characterized by the production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides. Common names: Autoimmune Diseases; Autoimmune Disease; Disease, Autoimmune; Diseases, Autoimmune |
Monday, November 23, 2009
17 Oct 2009
ZAP-70 is critical for T cell receptor (TCR) signaling. Tyrosine to phenylalanine mutations of Y315 and Y319 in ZAP-70 suggest these residues function to recruit downstream effector molecules, but mutagenesis and crystallization studies reveal that ... Read more...
14 Oct 2009
Interferon-gamma (IFN-gamma) is an important mediator of immunity and inflammation that utilizes the JAK-STAT signaling pathway to activate the STAT1 transcription factor. Many functions of IFN-gamma have been ascribed to direct STAT1-mediated ... Read more...
29 Sep 2009
Naturally arising regulatory T (Treg) cells express the transcription factor FoxP3, which critically controls the development and function of Treg cells. FoxP3 interacts with another transcription factor Runx1 (also known as AML1). Here, we showed ... Read more...
Latest indexed articles for 'Autoimmune Diseases - Immunology'
These are the very latest articles for this heading:
- A hypomorphic allele of ZAP-70 reveals a distinct thymic threshold for autoimmune disease versus autoimmune reactivity.
17 Oct 2009 - Cross-regulation of signaling pathways by interferon-gamma: implications for immune responses and autoimmune diseases.
14 Oct 2009 - Indispensable role of the Runx1-Cbfbeta transcription complex for in vivo-suppressive function of FoxP3+ regulatory T cells.
29 Sep 2009 - TLR3 ligand polyinosinic:polycytidylic acid induces IL-17A and IL-21 synthesis in human Th cells.
9 Sep 2009 - [The myelodysplastic syndrome and autoimmunity]
5 Sep 2009 - Complement regulators and inhibitory proteins.
2 Sep 2009 - The body as foe.
30 Aug 2009 - Unraveling the etiology of systemic autoimmune diseases: peering into the preclinical phase of disease.
30 Aug 2009 - Case of linear IgA bullous dermatosis-involved ulcerative colitis.
30 Aug 2009 - Enthesitis: an autoinflammatory lesion linking nail and joint involvement in psoriatic disease.
30 Aug 2009 - The functional network of ion channels in T lymphocytes.
30 Aug 2009 - CX3CR1-deficiency is associated with increased severity of disease in experimental autoimmune uveitis.
30 Aug 2009 - Drug-induced autoimmunity.
30 Aug 2009 - Anti-NMDA receptor antibodies encephalitis.
30 Aug 2009 - Sugar-free antibodies--the bacterial solution to autoimmunity?
30 Aug 2009 - Influenza and autoimmunity.
30 Aug 2009 - Microparticles and the hygiene hypothesis.
30 Aug 2009 - Regulatory B cells in autoimmune diseases: how do they work?
30 Aug 2009 - A new year in autoimmunity.
30 Aug 2009 - Seronegative autoimmune diseases.
30 Aug 2009
See a longer list of these articles.
Technical information about 'Autoimmune Diseases'
Definition: Disorders that are characterized by the production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides.
Descriptor UI: D001327
Alternative terms: Autoimmune Diseases; Autoimmune Disease; Disease, Autoimmune; Diseases, Autoimmune;
Related Mesh Headings: Autoantibodies; Autoimmunity;
Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;
Tree Number: C20.111;
Technical Notes: AUTOIMMUNE DISEASES OF THE NERVOUS SYSTEM is available