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B-Lymphocytes - Immunology
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Definition of 'B-Lymphocytes'

Lymphoid cells concerned with humoral immunity. They are short-lived cells resembling bursa-derived lymphocytes of birds in their production of immunoglobulin upon appropriate stimulation.

Common names: B-Lymphocytes; B Lymphocytes; B-Lymphocyte; Bursa-Dependent Lymphocytes; Bursa Dependent Lymphocytes; Bursa-Dependent Lymphocyte; Lymphocyte, Bursa-Dependent; Lymphocytes, Bursa-Dependent; B-Cells; B Cells; B-Cell

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Sunday, November 22, 2009

T cell-mediated control of Epstein-Barr virus infection in humanized mice.

13 Nov 2009 Humanized NOD/Shi-scid/interleukin-2Rgamma(null) (NOG) mice with full T cell development had significantly longer life span after Epstein-Barr virus (EBV) infection, compared with those with minimal T cell development. Removing CD3(+) or CD8(+) T ... Read more...


The shared tumor associated antigen cyclin-A2 is recognized by high-avidity T-cells.

13 Nov 2009 Cyclin-A2, a key cell cycle regulator, has been shown to be overexpressed in various types of malignancies with little expression in normal tissue. Such tumor-associated genes potentially are useful targets for cancer immunotherapy. However, ... Read more...


The follicular versus marginal zone B lymphocyte cell fate decision.

30 Oct 2009 Bone marrow-derived B cells make an important cell fate choice to develop into either follicular B cells or marginal zone B cells in the spleen, which depends on signalling through the B cell receptor, Notch2, the receptor for B cell-activating ... Read more...

 

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Technical information about 'B-Lymphocytes'

Definition: Lymphoid cells concerned with humoral immunity. They are short-lived cells resembling bursa-derived lymphocytes of birds in their production of immunoglobulin upon appropriate stimulation.

Descriptor UI: D001402

Alternative terms: B-Lymphocytes; B Lymphocytes; B-Lymphocyte; Bursa-Dependent Lymphocytes; Bursa Dependent Lymphocytes; Bursa-Dependent Lymphocyte; Lymphocyte, Bursa-Dependent; Lymphocytes, Bursa-Dependent; B-Cells; B Cells; B-Cell;

Related Mesh Headings: Lymphocyte Cooperation; Germinal Center;

Allowable Qualifiers: classification; cytology; drug effects; enzymology; immunology; metabolism; microbiology; parasitology; pathology; physiology; radiation effects; radiography; radionuclide imaging; secretion; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A11.063.438; A11.118.637.555.567.562; A15.145.229.637.555.567.562; A15.382.032.438; A15.382.490.555.567.562;

History Note: 90; was B LYMPHOCYTES 1973-89

Technical Notes: involved in antibody formation; do not confuse X ref B-CELLS with pancreatic B cells or beta cells (index under ISLANDS OF LANGERHANS); A 11 qualif; subpopulations = B-LYMPHOCYTE SUBSETS

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