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B-Lymphocytes
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Definition of 'B-Lymphocytes'

Lymphoid cells concerned with humoral immunity. They are short-lived cells resembling bursa-derived lymphocytes of birds in their production of immunoglobulin upon appropriate stimulation.

Common names: B-Lymphocytes; B Lymphocytes; B-Lymphocyte; Bursa-Dependent Lymphocytes; Bursa Dependent Lymphocytes; Bursa-Dependent Lymphocyte; Lymphocyte, Bursa-Dependent; Lymphocytes, Bursa-Dependent; B-Cells; B Cells; B-Cell

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Tuesday, November 24, 2009

Generation of a human immunodeficiency virus type 1 chronically infected monkey B cell line expressing low levels of endogenous TRIM5alpha.

29 Nov 2009 Several innate cellular antiviral factors exist in mammalian cells that prevent the replication of retroviruses. Among them, the tripartite motif protein (TRIM)5alpha has been shown to block human immunodeficiency virus type 1 (HIV-1) infection in ... Read more...


T cell-mediated control of Epstein-Barr virus infection in humanized mice.

13 Nov 2009 Humanized NOD/Shi-scid/interleukin-2Rgamma(null) (NOG) mice with full T cell development had significantly longer life span after Epstein-Barr virus (EBV) infection, compared with those with minimal T cell development. Removing CD3(+) or CD8(+) T ... Read more...


The shared tumor associated antigen cyclin-A2 is recognized by high-avidity T-cells.

13 Nov 2009 Cyclin-A2, a key cell cycle regulator, has been shown to be overexpressed in various types of malignancies with little expression in normal tissue. Such tumor-associated genes potentially are useful targets for cancer immunotherapy. However, ... Read more...

 

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Technical information about 'B-Lymphocytes'

Definition: Lymphoid cells concerned with humoral immunity. They are short-lived cells resembling bursa-derived lymphocytes of birds in their production of immunoglobulin upon appropriate stimulation.

Descriptor UI: D001402

Alternative terms: B-Lymphocytes; B Lymphocytes; B-Lymphocyte; Bursa-Dependent Lymphocytes; Bursa Dependent Lymphocytes; Bursa-Dependent Lymphocyte; Lymphocyte, Bursa-Dependent; Lymphocytes, Bursa-Dependent; B-Cells; B Cells; B-Cell;

Related Mesh Headings: Lymphocyte Cooperation; Germinal Center;

Allowable Qualifiers: classification; cytology; drug effects; enzymology; immunology; metabolism; microbiology; parasitology; pathology; physiology; radiation effects; radiography; radionuclide imaging; secretion; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A11.063.438; A11.118.637.555.567.562; A15.145.229.637.555.567.562; A15.382.032.438; A15.382.490.555.567.562;

History Note: 90; was B LYMPHOCYTES 1973-89

Technical Notes: involved in antibody formation; do not confuse X ref B-CELLS with pancreatic B cells or beta cells (index under ISLANDS OF LANGERHANS); A 11 qualif; subpopulations = B-LYMPHOCYTE SUBSETS

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