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B-Lymphocytes - Research News and Information

Thursday, January 08, 2009

Definition of 'B-Lymphocytes'

Lymphoid cells concerned with humoral immunity. They are short-lived cells resembling bursa-derived lymphocytes of birds in their production of immunoglobulin upon appropriate stimulation.

Common names: B-Lymphocytes; B Lymphocytes; B-Lymphocyte; Bursa-Dependent Lymphocytes; Bursa Dependent Lymphocytes; Bursa-Dependent Lymphocyte; Lymphocyte, Bursa-Dependent; Lymphocytes, Bursa-Dependent; B-Cells; B Cells; B-Cell

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Intratumoral rhIL-12 administration in head and neck squamous cell carcinoma patients induces B cell activation.

13 Nov 2008 The objectives of this study were to investigate the effects of intratumorally (i.t.) administered recombinant human interleukin-12 (rhIL-12) on the distribution and function of B cells in the primary tumors, the locoregional lymph nodes and ... Read more...


Balancing immunity and immunosuppression: vaccinating patients receiving treatment with efalizumab.

30 Oct 2008 Although effective in the treatment of immunodysregulatory diseases such as psoriasis, targeted immunosuppressive agents may confer risks of both enhanced susceptibility to infection and decreased responsiveness to vaccination. In a recent study, ... Read more...


Natalizumab disproportionately increases circulating pre-B and B cells in multiple sclerosis.

19 Oct 2008 BACKGROUND: Natalizumab, a humanized anti-alpha4 integrin monoclonal antibody, reduces relapses and disease progression in patients with multiple sclerosis (MS). Whereas its presumed mode of action is inhibition of T cell/monocyte entry into the ... Read more...

 

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Technical information about 'B-Lymphocytes'

Definition: Lymphoid cells concerned with humoral immunity. They are short-lived cells resembling bursa-derived lymphocytes of birds in their production of immunoglobulin upon appropriate stimulation.

Descriptor UI: D001402

Alternative terms: B-Lymphocytes; B Lymphocytes; B-Lymphocyte; Bursa-Dependent Lymphocytes; Bursa Dependent Lymphocytes; Bursa-Dependent Lymphocyte; Lymphocyte, Bursa-Dependent; Lymphocytes, Bursa-Dependent; B-Cells; B Cells; B-Cell;

Related Mesh Headings: Lymphocyte Cooperation; Germinal Center;

Allowable Qualifiers: classification; cytology; drug effects; enzymology; immunology; metabolism; microbiology; parasitology; pathology; physiology; radiation effects; radiography; radionuclide imaging; secretion; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A11.063.438; A11.118.637.555.567.562; A15.145.229.637.555.567.562; A15.382.032.438; A15.382.490.555.567.562;

History Note: 90; was B LYMPHOCYTES 1973-89

Technical Notes: involved in antibody formation; do not confuse X ref B-CELLS with pancreatic B cells or beta cells (index under ISLANDS OF LANGERHANS); A 11 qualif; subpopulations = B-LYMPHOCYTE SUBSETS

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