Base Pairing
Research News and Information

Sunday, November 22, 2009

The unstable part of the apical stem of duck hepatitis B virus epsilon shows enhanced base pair opening but not pico- to nanosecond dynamics and is essential for reverse transcriptase binding.

8 Nov 2009 Hepatitis B virus (HBV) replication starts with binding of reverse transcriptase (RT) to the apical stem-loop region of epsilon, a conserved element of the RNA pregenome. For duck HBV, an in vitro replication system has provided molecular details of ... Read more...

Mutational hot spot potential of a novel base pair mutation of the CSPG2 gene in a family with Wagner syndrome.

30 Oct 2009 OBJECTIVE: To report a 3-generation white family clinically diagnosed variably with Wagner, Stickler, and Jansen syndromes and screened for sequence variants in the COL2A1 and CSPG2 genes. Wagner syndrome is an autosomal dominant vitreoretinopathy ... Read more...

The cis-(5R,6S)-thymine glycol lesion occupies the wobble position when mismatched with deoxyguanosine in DNA.

18 Oct 2009 Oxidative damage to 5-methylcytosine in DNA, followed by deamination, yields thymine glycol (Tg), 5,6-dihydroxy-5,6-dihydrothymine, mispaired with deoxyguanosine. The structure of the 5R Tg.G mismatch pair has been refined using a combination of ... Read more...

Latest indexed articles for 'Base Pairing'

These are the very latest articles for this heading:

• The unstable part of the apical stem of duck hepatitis B virus epsilon shows enhanced base pair opening but not pico- to nanosecond dynamics and is essential for reverse transcriptase binding. 8 Nov 2009
• Mutational hot spot potential of a novel base pair mutation of the CSPG2 gene in a family with Wagner syndrome. 30 Oct 2009
• The cis-(5R,6S)-thymine glycol lesion occupies the wobble position when mismatched with deoxyguanosine in DNA. 18 Oct 2009
• Effect of GC base pairs on charge transfer through DNA hairpins: the importance of electrostatic interactions. 12 Oct 2009
• Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes. 6 Oct 2009
• Portability of the GN(R)A hairpin loop motif between RNA and DNA. 20 Sep 2009
• Ab initio study of the electron transfer in an ionized stacked complex of guanines. 8 Sep 2009
• Excited states of DNA base pairs using long-range corrected time-dependent density functional theory. 8 Sep 2009
• Blimp-1/Prdm1 alternative promoter usage during mouse development and plasma cell differentiation. 6 Sep 2009
• Extracellular signal-regulated kinase 1 (ERK1) and ERK2 play essential roles in osteoblast differentiation and in supporting osteoclastogenesis. 6 Sep 2009
• Comparison of the thermodynamics and base-pair dynamics of a full LNA:DNA duplex and of the isosequential DNA:DNA duplex. 6 Sep 2009
• Recognition of Phytophthora infestans Avr4 by potato R4 is triggered by C-terminal domains comprising W motifs. 30 Aug 2009
• Base flipping in V(D)J recombination: insights into the mechanism of hairpin formation, the 12/23 rule, and the coordination of double-strand breaks. 29 Aug 2009
• New metrics for comparing and assessing discrepancies between RNA 3D structures and models. 24 Aug 2009
• MutS and UvrD proteins stimulate exonuclease action: insights into exonuclease-mediated strand repair. 23 Aug 2009
• A rare nucleotide base tautomer in the structure of an asymmetric DNA junction. 23 Aug 2009
• Non-canonical RNA arrangement in T4-even phages: accommodated ribosome binding site at the gene 26-25 intercistronic junction. 22 Aug 2009
• Mrd1p is required for release of base-paired U3 snoRNA within the preribosomal complex. 22 Aug 2009
• Influence of hydration on proton transfer in the guanine-cytosine radical cation (G*+-C) base pair: a density functional theory study. 18 Aug 2009
• A novel G6PC3 homozygous 1-bp deletion as a cause of severe congenital neutropenia. 18 Aug 2009

See a longer list of these articles.

Technical information about 'Base Pairing'

Definition: Pairing of purine and pyrimidine bases by HYDROGEN BONDING in double-stranded DNA or RNA.

Descriptor UI: D020029

Alternative terms: Base Pairing; Base Pairings; Base Pair; Base Pairs;

Related Mesh Headings: Base Composition; Base Pair Mismatch;

Allowable Qualifiers: drug effects; genetics; physiology; radiation effects; ethics;

Tree Number: G02.111.087.620.500; G02.111.570.790.486.100; G02.149.115.620.500; G05.360.580.100;

History Note: 99; use BASE COMPOSITION 1980-98

Technical Notes: coord with DNA or RNA or specific