Basophil Degranulation Test - Methods
Research News and Information

Monday, November 23, 2009

The basophil activation test in immediate-type drug allergy.

30 Jul 2009 Diagnosis of drug allergy involves first the recognition of sometimes unusual symptoms as drug allergy and, second, the identification of the eliciting drug. This is an often difficult task, as the clinical picture and underlying pathomechanisms are ... Read more...

[The usefulness of CD203c expression measurement on basophils after activation with grass pollen and Dermatophagoides pteronyssinus antigens. Preliminary study]

30 Dec 2008 INTRODUCTION: 'Gold standard' in the diagnosis of atopic disease are skin prick tests and specific IgE evaluation. Well-established in vitro tests, such as the histamine release test, the leukotriens release test and the flow cytometric basophil ... Read more...

[Flow cytometric basophils activation test as a method of allergy diagnosis]

30 Dec 2008 For several years the incidences of allergic diseases and anaphylactic reactions have been increasing dramatically. Classical method of allergy diagnosis - skin prick test in some situations can provoke life-threatening reactions. Detection of ... Read more...

Latest indexed articles for 'Basophil Degranulation Test - Methods'

These are the very latest articles for this heading:

• The basophil activation test in immediate-type drug allergy. 30 Jul 2009
• Studying specific IgE: in vivo or in vitro. 30 Dec 2008
• [The usefulness of CD203c expression measurement on basophils after activation with grass pollen and Dermatophagoides pteronyssinus antigens. Preliminary study] 30 Dec 2008
• [Flow cytometric basophils activation test as a method of allergy diagnosis] 30 Dec 2008
• An IL-1 cytokine member, IL-33, induces human basophil activation via its ST2 receptor. 30 Oct 2008
• [Basophil activation test as in vitro assay for cisplatin allergy] 30 Oct 2008
• Basophil activation test for the in vitro diagnosis of nonsteroidal anti-inflammatory drug hypersensitivity. 29 Apr 2008
• Chronic idiopathic urticaria: comparison of clinical features with positive autologous serum skin test. 28 Feb 2008
• Diagnostic tests based on human basophils: more potentials and perspectives than pitfalls. 9 Feb 2008
• Cellular tests in the diagnosis of drug hypersensitivity. 30 Dec 2007
• Diagnostic tests based on human basophils: more potentials and perspectives than pitfalls. II. Technical issues. 30 Dec 2007
• Flow cytometry for basophil activation markers: the measurement of CD203c up-regulation is as reliable as CD63 expression in the diagnosis of cat allergy. 2007
• Comparision of two-flow cytometry methods for basophil degranulation in patients sensitized to grass pollen. 30 Aug 2006
• The use of basophil activation to diagnose allergy to Gelofusine. 29 Jun 2006
• [Drug allergy assessed by modified Shelley's test. A case series] 29 Apr 2006
• Anaphylaxis to Gelofusine confirmed by in vitro basophil activation test: a case series. 27 Feb 2006
• Diagnosis of neuromuscular blocking agent hypersensitivity reactions using cytofluorimetric analysis of basophils. 27 Feb 2006
• Replication study concerning the effects of homeopathic dilutions of histamine on human basophil degranulation in vitro. 30 May 2005
• No evidence of increased serum substance P levels in chronic urticaria patients with and without demonstrable circulating vasoactive factors. 27 Feb 2005
• [Basophil activation tests in the diagnosis of drug reactions] 30 Dec 2004

See a longer list of these articles.

Technical information about 'Basophil Degranulation Test'

Definition: An in vitro test used in the diagnosis of allergies including drug hypersensitivity. The allergen is added to the patient's white blood cells and the subsequent histamine release is measured.

Descriptor UI: D015549

Alternative terms: Basophil Degranulation Test; Basophil Degranulation Tests; Degranulation Test, Basophil; Degranulation Tests, Basophil;

Allowable Qualifiers: adverse effects; classification; economics; history; instrumentation; methods; mortality; nursing; psychology; standards; trends; utilization; veterinary; statistics & numerical data; contraindications; ethics;

Tree Number: E01.450.495.100; E05.478.594.100;

History Note: 91(90); was see under IMMUNOLOGIC TESTS 1990

Technical Notes: do not use /util except by MeSH definition