Basophils - Immunology
Research News and Information

Sunday, November 22, 2009

Basophils can directly present or cross-present antigen to CD8 lymphocytes and alter CD8 T cell differentiation into IL-10-producing phenotypes.

8 Aug 2009 There is increasing evidence suggesting that basophils play a critical role in developing Th2-type immunity both in vitro and in vivo. We previously reported that basophils cocultured with naive CD4 T cells stimulated with Ag promote the ... Read more...

The basophil activation test in immediate-type drug allergy.

30 Jul 2009 Diagnosis of drug allergy involves first the recognition of sometimes unusual symptoms as drug allergy and, second, the identification of the eliciting drug. This is an often difficult task, as the clinical picture and underlying pathomechanisms are ... Read more...

Haemopoietic processes in allergic disease: eosinophil/basophil development.

18 Jul 2009 Haemopoietic myeloid progenitors contribute to the ongoing recruitment of pro-inflammatory cells, such as eosinophils and basophils (Eo/B), to target tissue sites in allergic diseases. It is apparent that the development of allergic inflammation is ... Read more...

Latest indexed articles for 'Basophils - Immunology'

These are the very latest articles for this heading:

• Editorial: Basophil survival and immunomodulatory function are uniquely regulated by a novel MyD88-dependent pathway. 29 Sep 2009
• Basophils can directly present or cross-present antigen to CD8 lymphocytes and alter CD8 T cell differentiation into IL-10-producing phenotypes. 8 Aug 2009
• The basophil activation test in immediate-type drug allergy. 30 Jul 2009
• Haemopoietic processes in allergic disease: eosinophil/basophil development. 18 Jul 2009
• The non-specific lipid transfer protein, Ara h 9, is an important allergen in peanut. 14 Jul 2009
• Exploring the repertoire of IgE-binding self-antigens associated with atopic eczema. 7 Jul 2009
• Clinical efficacy and immune regulation with peanut oral immunotherapy. Jul 2009
• Basophil responsiveness in chronic urticaria. 29 Jun 2009
• New concepts of hive formation in cholinergic urticaria. 29 Jun 2009
• Basophils trump dendritic cells as APCs for T(H)2 responses. 29 Jun 2009
• Immunoglobulin D enhances immune surveillance by activating antimicrobial, proinflammatory and B cell-stimulating programs in basophils. 26 Jun 2009
• Inhibitory effects of flavonoids isolated from Fragaria ananassa Duch on IgE-mediated degranulation in rat basophilic leukemia RBL-2H3. 25 Jun 2009
• Human innate immunosenescence: causes and consequences for immunity in old age. 19 Jun 2009
• A novel nanoparticulate adjuvant for immunotherapy with Lolium perenne. 19 Jun 2009
• Basophils contribute to T(H)2-IgE responses in vivo via IL-4 production and presentation of peptide-MHC class II complexes to CD4+ T cells. 22 May 2009
• Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response. 22 May 2009
• MHC class II-dependent basophil-CD4+ T cell interactions promote T(H)2 cytokine-dependent immunity. 22 May 2009
• IL-18 and IL-33 elicit Th2 cytokines from basophils via a MyD88- and p38alpha-dependent pathway. 16 May 2009
• Self-termination/anergic mechanisms in human basophils and mast cells. 9 May 2009
• Pathogenesis of chronic urticaria. 20 Apr 2009

See a longer list of these articles.

Technical information about 'Basophils'

Definition: Granular leukocytes characterized by a relatively pale-staining, lobate nucleus and cytoplasm containing coarse dark-staining granules of variable size and stainable by basic dyes.

Descriptor UI: D001491

Alternative terms: Basophils; Basophil;

Allowable Qualifiers: classification; cytology; drug effects; enzymology; immunology; metabolism; microbiology; parasitology; pathology; physiology; radiation effects; radiography; radionuclide imaging; secretion; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A11.118.637.415.120; A11.627.340.120; A15.145.229.637.415.120; A15.382.490.315.120;

Technical Notes: restrict to leukocytes: not for "basophilic" when referring only to staining ( = STAINING)