Basophils - Metabolism
Research News and Information

Sunday, November 22, 2009

SHIP represses the generation of IL-3-induced M2 macrophages by inhibiting IL-4 production from basophils.

24 Aug 2009 There is a great deal of interest in determining what regulates the generation of classically activated (M1) vs alternatively activated (M2) macrophages (Mphis) because of the opposing effects that these two Mphi subsets have on tumor progression. ... Read more...

Basophils can directly present or cross-present antigen to CD8 lymphocytes and alter CD8 T cell differentiation into IL-10-producing phenotypes.

8 Aug 2009 There is increasing evidence suggesting that basophils play a critical role in developing Th2-type immunity both in vitro and in vivo. We previously reported that basophils cocultured with naive CD4 T cells stimulated with Ag promote the ... Read more...

The basophil activation test in immediate-type drug allergy.

30 Jul 2009 Diagnosis of drug allergy involves first the recognition of sometimes unusual symptoms as drug allergy and, second, the identification of the eliciting drug. This is an often difficult task, as the clinical picture and underlying pathomechanisms are ... Read more...

Latest indexed articles for 'Basophils - Metabolism'

These are the very latest articles for this heading:

• SHIP represses the generation of IL-3-induced M2 macrophages by inhibiting IL-4 production from basophils. 24 Aug 2009
• Basophils can directly present or cross-present antigen to CD8 lymphocytes and alter CD8 T cell differentiation into IL-10-producing phenotypes. 8 Aug 2009
• The basophil activation test in immediate-type drug allergy. 30 Jul 2009
• STAT1 negatively regulates lung basophil IL-4 expression induced by respiratory syncytial virus infection. 6 Jul 2009
• Basophil responsiveness in chronic urticaria. 29 Jun 2009
• Immunoglobulin D enhances immune surveillance by activating antimicrobial, proinflammatory and B cell-stimulating programs in basophils. 26 Jun 2009
• Human innate immunosenescence: causes and consequences for immunity in old age. 19 Jun 2009
• A novel nanoparticulate adjuvant for immunotherapy with Lolium perenne. 19 Jun 2009
• The binding specificity and selective antagonism of vedolizumab, an anti-alpha4beta7 integrin therapeutic antibody in development for inflammatory bowel diseases. 7 Jun 2009
• Functional role of human NK cell receptor 2B4 (CD244) isoforms. 30 May 2009
• Basophils contribute to T(H)2-IgE responses in vivo via IL-4 production and presentation of peptide-MHC class II complexes to CD4+ T cells. 22 May 2009
• Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response. 22 May 2009
• MHC class II-dependent basophil-CD4+ T cell interactions promote T(H)2 cytokine-dependent immunity. 22 May 2009
• Early signal protein expression profiles in basophils: a population study. 10 May 2009
• Self-termination/anergic mechanisms in human basophils and mast cells. 9 May 2009
• Pathogenesis of chronic urticaria. 20 Apr 2009
• Expression of the high affinity IgE receptor by neutrophils of individuals with allergic asthma is both minimal and insensitive to regulation by serum IgE. 6 Apr 2009
• The change of asthma-associated immunological parameters in children with Mycoplasma pneumoniae infection. 30 Mar 2009
• Effect of heat treatment and enzymatic digestion on the B cell epitopes of cow's milk proteins. 8 Mar 2009
• Diagnosing immune-mediated reactions to drugs. 27 Feb 2009

See a longer list of these articles.

Technical information about 'Basophils'

Definition: Granular leukocytes characterized by a relatively pale-staining, lobate nucleus and cytoplasm containing coarse dark-staining granules of variable size and stainable by basic dyes.

Descriptor UI: D001491

Alternative terms: Basophils; Basophil;

Allowable Qualifiers: classification; cytology; drug effects; enzymology; immunology; metabolism; microbiology; parasitology; pathology; physiology; radiation effects; radiography; radionuclide imaging; secretion; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A11.118.637.415.120; A11.627.340.120; A15.145.229.637.415.120; A15.382.490.315.120;

Technical Notes: restrict to leukocytes: not for "basophilic" when referring only to staining ( = STAINING)