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Behavior, Addictive - Physiopathology
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Definition of 'Behavior, Addictive'

The observable, measurable, and often pathological activity of an organism that portrays its inability to overcome a habit resulting in an insatiable craving for a substance or for performing certain acts. The addictive behavior includes the emotional and physical overdependence on the object of habit in increasing amount or frequency.

Common names: Behavior, Addictive; Addictive Behavior; Addictive Behaviors; Behaviors, Addictive

More technical Information...

Monday, November 23, 2009

Deficits in substance P mRNA levels in the CeA are inversely associated with alcohol-motivated responding.

30 Oct 2009 In the present study, in vitro and in vivo studies were conducted to determine the relationship between innate substance P (SP) levels and alcohol-motivated behavior in alcohol-preferring (P) and nonpreferring (NP) rat lines. In Experiment 1, in ... Read more...


Orexin/hypocretin signaling at the orexin 1 receptor regulates cue-elicited cocaine-seeking.

26 Jul 2009 The orexin/hypocretin system has recently been implicated in reward-processing and addiction. We examined the involvement of the orexin system in cue-induced reinstatement of extinguished cocaine-seeking by administering the orexin 1 receptor ... Read more...


Upregulation of GLT1 attenuates cue-induced reinstatement of cocaine-seeking behavior in rats.

20 Jul 2009 Relapse to cocaine-seeking behavior depends on increased glutamate transmission in key regions of the mesocorticolimbic motive circuit, including prefrontal cortex (PFC) and nucleus accumbens (NAcc). Because GLT1 is responsible for the uptake of ... Read more...

 

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Technical information about 'Behavior, Addictive'

Definition: The observable, measurable, and often pathological activity of an organism that portrays its inability to overcome a habit resulting in an insatiable craving for a substance or for performing certain acts. The addictive behavior includes the emotional and physical overdependence on the object of habit in increasing amount or frequency.

Descriptor UI: D016739

Alternative terms: Behavior, Addictive; Addictive Behavior; Addictive Behaviors; Behaviors, Addictive;

Related Mesh Headings: Substance-Related Disorders;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; diagnosis; diet therapy; drug therapy; economics; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; rehabilitation; surgery; therapy; urine; ultrasonography; virology;

Tree Number: F01.145.527.100.120;

History Note: 92

Technical Notes: use Cat F3 qualif

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