Benzazepines - Research News and Information

Thursday, January 08, 2009

Regulation of synaptic efficacy in hypocretin/orexin-containing neurons by melanin concentrating hormone in the lateral hypothalamus.

8 Sep 2008 The lateral hypothalamus (LH) is a central hub that integrates inputs from, and sends outputs to, many other brain areas. Two groups of neurons in the LH, expressing hypocretin/orexin or melanin concentrating hormone (MCH), have been shown to ... Read more...

Neuropsychiatric disturbance after initiation of varenicline in a patient with a history of alcohol abuse and major depression.

30 Aug 2008 PURPOSE: The case of a patient with a history of alcohol abuse and major depression who developed neuropsychiatric symptoms after initiation of varenicline is reported. SUMMARY: A 33-year-old Caucasian man was prescribed varenicline for smoking ... Read more...

Dopamine D5 receptors: a challenge to medicinal chemists.

30 Aug 2008 Due to the lack of highly selective dopamine D(1) or D(5) receptor ligands, only few data about activation or blocking of these receptor subtypes are available. The present review collects the available information about molecules with notable ... Read more...

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Latest indexed articles for 'Benzazepines'

These are the very latest articles for this heading:

• [Varenicline for smoking cessation] 9 Sep 2008
• Regulation of synaptic efficacy in hypocretin/orexin-containing neurons by melanin concentrating hormone in the lateral hypothalamus. 8 Sep 2008
• Neuropsychiatric disturbance after initiation of varenicline in a patient with a history of alcohol abuse and major depression. 30 Aug 2008
• Chronic stable angina pectoris. 30 Aug 2008
• Varenicline and suicidality: a new era in medication safety surveillance. 30 Aug 2008
• Dopamine D5 receptors: a challenge to medicinal chemists. 30 Aug 2008
• First in class. 30 Aug 2008
• Characterization of the heart rate-lowering action of ivabradine, a selective I(f) current inhibitor. 30 Aug 2008
• Ivabradine for patients with stable coronary artery disease and left-ventricular systolic dysfunction (BEAUTIFUL): a randomised, double-blind, placebo-controlled trial. 27 Aug 2008
• Heart rate as a prognostic risk factor in patients with coronary artery disease and left-ventricular systolic dysfunction (BEAUTIFUL): a subgroup analysis of a randomised controlled trial. 27 Aug 2008
• BEAUTIFUL results--the slower, the better? 27 Aug 2008
• Novel 2,4-methanoadamantane-benzazepine by domino photochemistry of N-(1-adamantyl)phthalimide. 19 Aug 2008
• Dopaminergic D1 and D2 receptors are essential for the arousal effect of modafinil. 18 Aug 2008
• Three styryl-substituted tetrahydro-1,4-epoxy-1-benzazepines: configurations, conformations and hydrogen-bonded chains. 17 Aug 2008
• Three aryl-substituted tetrahydro-1,4-epoxy-1-benzazepines: hydrogen-bonded structures in two or three dimensions. 17 Aug 2008
• Three tetrahydro-1,4-epoxy-1-benzazepines carrying pendent heterocyclic substituents: supramolecular structures in zero, one or two dimensions. 17 Aug 2008
• Structural analysis of a holoenzyme complex of mouse dihydrofolate reductase with NADPH and a ternary complex with the potent and selective inhibitor 2,4-diamino-6-(2'-hydroxydibenz[b,f]azepin-5-yl)methylpteridine. 11 Aug 2008
• Neuropeptide Y receptors in primary human brain tumors: overexpression in high-grade tumors. 30 Jul 2008
• The place of varenicline in smoking cessation treatment. 30 Jul 2008
• Pre-cessation varenicline treatment vs post-cessation NRT: an uneven playing field. 30 Jul 2008

See a longer list of these articles.

Technical information about 'Benzazepines'

Definition: Compounds with BENZENE fused to AZEPINES.

Registry Number: 0

Descriptor UI: D001552

Alternative terms: Benzazepines;

Related Mesh Headings: Azepines; Dibenzazepines;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D03.438.079;

History Note: 68