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Benzazepines
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Definition of 'Benzazepines'

Compounds with BENZENE fused to AZEPINES.

Common names: Benzazepines

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Saturday, November 21, 2009

Indolobenzazepin-7-ones and 6-, 8-, and 9-membered ring derivatives as tubulin polymerization inhibitors: synthesis and structure--activity relationship studies.

6 Oct 2009 Several small weight indole derivatives (D-64131, D-24851, BPR0L075, BLF 61-3, and ATI derivatives) are potent tubulin polymerization inhibitors and show nanomolar antiproliferative activity. Among them, indolobenzazepin-7-ones were recently ... Read more...


Varenicline and suicidal behaviour: a cohort study based on data from the General Practice Research Database.

29 Sep 2009 OBJECTIVE: To determine whether varenicline, a recently licensed smoking cessation product, is associated with an increased risk of suicide and suicidal behaviour compared with alternative treatments bupropion and nicotine replacement therapy. ... Read more...


Regulation of dynamin 2 and G protein-coupled receptor kinase 2 in rat nucleus accumbens during acute and repeated cocaine administration.

29 Sep 2009 Exposure to cocaine causes many neuroadaptations including alterations in several neurotransmitter receptors and transporters. This study investigated potential mechanisms of cocaine-induced receptor and transporter regulation by measuring levels of ... Read more...

 

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Technical information about 'Benzazepines'

Definition: Compounds with BENZENE fused to AZEPINES.

Registry Number: 0

Descriptor UI: D001552

Alternative terms: Benzazepines;

Related Mesh Headings: Azepines; Dibenzazepines;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D03.438.079;

History Note: 68

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