Benzenesulfonates - Research News and Information

Thursday, January 08, 2009

Sorafenib for older patients with renal cell carcinoma: subset analysis from a randomized trial.

5 Oct 2008 BACKGROUND: The perception that older cancer patients may be at higher risk than younger patients of toxic effects from cancer therapy but may obtain less clinical benefit from it may be based on the underrepresentation of older patients in ... Read more...

Characterization of pharmacologically active compounds that inhibit poliovirus and enterovirus 71 infectivity.

29 Sep 2008 Poliovirus (PV) and enterovirus 71 (EV71) cause severe neurological symptoms in their infections of the central nervous system. To identify compounds with anti-PV and anti-EV71 activities that would not allow the emergence of resistant mutants, we ... Read more...

Molecular targeted therapies in hepatocellular carcinoma.

29 Sep 2008 Hepatocellular carcinoma (HCC) is a complex and heterogeneous tumor with several genomic alterations. There is evidence of aberrant activation of several signaling cascades such as epidermal growth factor receptor (EGFR), Ras/extracellular ... Read more...

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Latest indexed articles for 'Benzenesulfonates'

These are the very latest articles for this heading:

• Sorafenib for older patients with renal cell carcinoma: subset analysis from a randomized trial. 5 Oct 2008
• Characterization of pharmacologically active compounds that inhibit poliovirus and enterovirus 71 infectivity. 29 Sep 2008
• Molecular targeted therapies in hepatocellular carcinoma. 29 Sep 2008
• Dynamic contrast-enhanced magnetic resonance imaging pharmacodynamic biomarker study of sorafenib in metastatic renal carcinoma. 29 Sep 2008
• [Anti-angiogenic treatment in the management of metastatic renal cell carcinoma] 29 Sep 2008
• Preclinical overview of sorafenib, a multikinase inhibitor that targets both Raf and VEGF and PDGF receptor tyrosine kinase signaling. 29 Sep 2008
• Preclinical evaluation of dasatinib, a potent Src kinase inhibitor, in melanoma cell lines. 27 Sep 2008
• Sunitinib-induced macrocytosis in patients with metastatic renal cell carcinoma. 13 Sep 2008
• Assessment of the suitability of Tinopal as an enhancing adjuvant in formulations of the insect pathogenic fungus Beauveria bassiana (Bals.) Vuillemin. 30 Aug 2008
• Targeted therapy in renal cell carcinoma. 30 Aug 2008
• Vorinostat and sorafenib synergistically kill tumor cells via FLIP suppression and CD95 activation. 30 Aug 2008
• [Renal cell carcinoma] 30 Aug 2008
• Major treatment improvements encourage kidney cancer researchers to seek further gains. 24 Aug 2008
• Acute exacerbation of hemorrhagic rectocolitis during antiangiogenic therapy with sunitinib and sorafenib. 20 Aug 2008
• Using enantioselective indicator displacement assays to determine the enantiomeric excess of alpha-amino acids. 19 Aug 2008
• Sorafenib: tolerance in patients on chronic hemodialysis: a single-center experience. 19 Aug 2008
• Secondary erythrocytosis produced by the tyrosine kinase inhibitors sunitinib and sorafenib. 18 Aug 2008
• Prospective comparison of sorafenib and sunitinib for second-line treatment of cytokine-refractory kidney cancer patients. 18 Aug 2008
• Effect of rapamycin alone and in combination with sorafenib in an orthotopic model of human hepatocellular carcinoma. 13 Aug 2008
• Watchdog set to reject four drugs for kidney cancer on the NHS. 12 Aug 2008

See a longer list of these articles.

Technical information about 'Benzenesulfonates'

Definition: Organic salts and esters of benzenesulfonic acid.

Registry Number: 0

Descriptor UI: D001557

Alternative terms: Benzenesulfonates;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D02.455.426.559.389.097; D02.886.645.600.080.050.100;

History Note: 74