Benzoxazines - Chemistry
Research News and Information

Thursday, March 18, 2010

Aromatic-ring-functionalised benzoxazinones in the system Oryza sativa-Echinochloa crus-galli as biorational herbicide models.

29 Sep 2009 BACKGROUND: Barnyardgrass, Echinochloa crus-galli (L.) Beauv., is one of the most problematic weeds occurring in rice crops. Although efficient chemical control is provided by herbicides available on the market, resistant biotypes provoked by ... Read more...

Reactions of ortho-lithiophenyl (-hetaryl) isocyanides with carbonyl compounds: rearrangements of 2-metalated 4H-3,1-benzoxazines.

17 Jun 2009 ortho-Lithiophenyl (-hetaryl) isocyanides react with aldehydes and ketones providing isocyanoalcohols 8 (36-89%, nine examples), 4H-3,1-benzoxazines 9 (45-78%, six examples) or, after two types of rearrangements, isobenzofuran-1(3H)-imines ... Read more...

Synthesis and optimization of 2-pyridin-3-yl-benzo[d][1,3]oxazin-4-one based inhibitors of human neutrophil elastase.

15 Jun 2009 The hit-to-lead optimization of the HNE inhibitor 5-methyl-2-(2-phenoxy-pyridin-3-yl)-benzo[d][1,3]oxazin-4-one is described. A structure-activity relationship study that focused on the 5 and 7 benzoxazinone positions yielded the optimized ... Read more...

Latest indexed articles for 'Benzoxazines - Chemistry'

These are the very latest articles for this heading:

• Aromatic-ring-functionalised benzoxazinones in the system Oryza sativa-Echinochloa crus-galli as biorational herbicide models. 29 Sep 2009
• Reactions of ortho-lithiophenyl (-hetaryl) isocyanides with carbonyl compounds: rearrangements of 2-metalated 4H-3,1-benzoxazines. 17 Jun 2009
• Synthesis and optimization of 2-pyridin-3-yl-benzo[d][1,3]oxazin-4-one based inhibitors of human neutrophil elastase. 15 Jun 2009
• Highly efficient copper-catalyzed domino ring opening and Goldberg coupling cyclization for the synthesis of 3,4-dihydro-2H-1,4-benzoxazines. 5 May 2009
• New approach for local structure analysis of the tyrosine domain in proteins by using a site-specific and polarity-sensitive fluorescent probe. 2 May 2009
• Bulky 1,4-benzoxazine derivatives with antifungal activity. May 2009
• 5,7,8-Trimethyl-benzopyran and 5,7,8-trimethyl-1,4-benzoxazine aminoamide derivatives as novel antiarrhythmics against ischemia-reperfusion injury. 21 Apr 2009
• A new resorufin-based alpha-glucosidase assay for high-throughput screening. 12 Apr 2009
• Copper(I)-catalyzed one-pot synthesis of 2H-1,4-benzoxazin-3-(4H)-ones from o-halophenols and 2-chloroacetamides. Apr 2009
• Rediscovering the bioactivity and ecological role of 1,4-benzoxazinones. 30 Mar 2009
• Simultaneous quantification of a non-nucleoside reverse transcriptase inhibitor efavirenz, a nucleoside reverse transcriptase inhibitor emtricitabine and a nucleotide reverse transcriptase inhibitor tenofovir in plasma by liquid chromatography positive ion electrospray tandem mass spectrometry. 30 Mar 2009
• In vivo analysis of efavirenz metabolism in individuals with impaired CYP2A6 function. 30 Mar 2009
• Protective effects of a benzoxazine derivative against oxidized LDL-induced apoptosis and the increases of integrin beta4, ROS, NF-kappaB and P53 in human umbilical vein endothelial cells. 19 Mar 2009
• 8-[2-(4-Aryl-1-piperazinyl)ethyl]-2H-1,4-benzoxazin-3(4H)-ones: dual-acting 5-HT1 receptor antagonists and serotonin reuptake inhibitors--part II. 18 Feb 2009
• Allelochemicals in rye (Secale cereale L.): cultivar and tissue differences in the production of benzoxazinoids and phenolic acids. 30 Jan 2009
• Physicochemical characterization of efavirenz-cyclodextrin inclusion complexes. 14 Jan 2009
• Voltammetric studies on the HIV-1 inhibitory drug Efavirenz: the interaction between dsDNA and drug using electrochemical DNA biosensor and adsorptive stripping voltammetric determination on disposable pencil graphite electrode. 7 Dec 2008
• An expeditious synthesis of benzoxazine-2-thione c-nucleosides Via Cu(OTf)2-mediated dehydrazinative beta-glycosylation. 29 Nov 2008
• Modified benzoxazinones in the system Oryza sativa-Echinochloa crus-galli: an approach to the development of biorational herbicide models. 14 Oct 2008
• Multicomponent synthesis of benzoxazinones via tandem Ugi/Mitsunobu reactions: an unexpected cine-substitution. 31 Aug 2008

See a longer list of these articles.

Technical information about 'Benzoxazines'

Definition: OXAZINES with a fused BENZENE ring.

Registry Number: 0

Descriptor UI: D048588

Alternative terms: Benzoxazines; Benzoxazinones; Benzoxazinoids;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D03.383.533.249; D03.438.209;

History Note: 2005

Technical Notes: do not confuse with benzoxazolines (index BENZOXAZOLES)