beta Catenin
Research News and Information

Sunday, November 22, 2009

Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway.

29 Nov 2009 Calcium/calmodulin-dependent protein kinase IV (CaMKIV) plays a key role in the regulation of calcium-dependent gene expression. The expression of CaMKIV and the activation of CREB regulated genes are involved in memory and neuronal survival. We ... Read more...

The anti-helminthic niclosamide inhibits Wnt/Frizzled1 signaling.

Nov 2009 Wnt proteins bind to seven-transmembrane Frizzled receptors to mediate the important developmental, morphogenetic, and stem cell related tissue-regenerative effects of Wnt signaling. Dysregulated Wnt signaling is associated with many cancers. ... Read more...

TSPAN12 regulates retinal vascular development by promoting Norrin- but not Wnt-induced FZD4/beta-catenin signaling.

14 Oct 2009 Mutations in the genes encoding the Wnt receptor Frizzled-4 (FZD4), coreceptor LRP5, or the ligand Norrin disrupt retinal vascular development and cause ophthalmic diseases. Although Norrin is structurally unrelated to Wnts, it binds FZD4 and ... Read more...

Latest indexed articles for 'beta Catenin'

These are the very latest articles for this heading:

• Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway. 29 Nov 2009
• The anti-helminthic niclosamide inhibits Wnt/Frizzled1 signaling. Nov 2009
• TSPAN12 regulates retinal vascular development by promoting Norrin- but not Wnt-induced FZD4/beta-catenin signaling. 14 Oct 2009
• Overexpression of the novel oncogene SALL4 and activation of the Wnt/beta-catenin pathway in myelodysplastic syndromes. 13 Oct 2009
• Increased expression of ErbB-2 in liver is associated with hepatitis B x antigen and shorter survival in patients with liver cancer. 13 Oct 2009
• Beta-catenin is involved in alterations in mitochondrial activity in non-transformed intestinal epithelial and colon cancer cells. 11 Oct 2009
• Convergence of 3',5'-cyclic adenosine 5'-monophosphate/protein kinase A and glycogen synthase kinase-3beta/beta-catenin signaling in corpus luteum progesterone synthesis. 7 Oct 2009
• Alzheimer's disease affects progenitor cells through aberrant {beta}-catenin signaling. 5 Oct 2009
• Drug discovery: Propping up a destructive regime. 29 Sep 2009
• Regulation of CDX2 expression in esophageal adenocarcinoma. 29 Sep 2009
• Regulation of peroxisome proliferator-activated receptor-beta/delta by the APC/beta-CATENIN pathway and nonsteroidal antiinflammatory drugs. 29 Sep 2009
• Epigenetic modulation of the retinoid X receptor alpha by green tea in the azoxymethane-Apc Min/+ mouse model of intestinal cancer. 29 Sep 2009
• A directional Wnt/beta-catenin-Sox2-proneural pathway regulates the transition from proliferation to differentiation in the Xenopus retina. 29 Sep 2009
• The posteriorizing gene Gbx2 is a direct target of Wnt signalling and the earliest factor in neural crest induction. 29 Sep 2009
• Inhibition of glycogen synthase kinase-3beta attenuates glucocorticoid-induced bone loss. 23 Sep 2009
• Lymphoid enhancer binding factor 1 regulates transcription through gene looping. 23 Sep 2009
• Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling. 14 Sep 2009
• Expression analysis of E-cadherin, Slug and GSK3beta in invasive ductal carcinoma of breast. 12 Sep 2009
• beta-Catenin promotes respiratory progenitor identity in mouse foregut. 7 Sep 2009
• Mesenchymal stem cells produce Wnt isoforms and TGF-beta1 that mediate proliferation and procollagen expression by lung fibroblasts. 2 Sep 2009

See a longer list of these articles.

Technical information about 'beta Catenin'

Definition: A multi-functional catenin that participates in CELL ADHESION and nuclear signaling. Beta catenin binds CADHERINS and helps link their cytoplasmic tails to the ACTIN in the CYTOSKELETON via ALPHA CATENIN. It also serves as a transcriptional co-activator and downstream component of WNT PROTEIN-mediated SIGNAL TRANSDUCTION PATHWAYS.

Registry Number: 0

Descriptor UI: D051176

Alternative terms: beta Catenin; Catenin, beta; beta-Catenin;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D12.776.091.249; D12.776.220.145.500; D12.776.930.130;

History Note: 2006(1992)