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Biogenic Amines - Metabolism
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Definition of 'Biogenic Amines'

A group of naturally occurring amines derived by enzymatic decarboxylation of the natural amino acids. Many have powerful physiological effects (e.g., histamine, serotonin, epinephrine, tyramine). Those derived from aromatic amino acids, and also their synthetic analogs (e.g., amphetamine), are of use in pharmacology.

Common names: Biogenic Amines; Biogenic Amine; Amine, Biogenic; Amines, Biogenic

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Monday, November 23, 2009

Combinational chelation therapy abrogates lead-induced neurodegeneration in rats.

8 Jul 2009 Lead, a ubiquitous and potent neurotoxicant causes oxidative stress which leads to numerous neurobehavioral and physiological alterations. The ability of lead to bind sulfhydryl groups or compete with calcium could be one of the reasons for its ... Read more...


Ligand-gated chloride channels are receptors for biogenic amines in C. elegans.

Jul 2009 Biogenic amines such as serotonin and dopamine are intercellular signaling molecules that function widely as neurotransmitters and neuromodulators. We have identified in the nematode Caenorhabditis elegans three ligand-gated chloride channels that ... Read more...


Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines.

29 Jun 2009 Kynuramines represent their own class of biogenic amines. They are formed either by decarboxylation of kynurenines or pyrrole ring cleavage of indoleamines. N(2)-formylated compounds formed in this last reaction can be deformylated either ... Read more...

 

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Technical information about 'Biogenic Amines'

Definition: A group of naturally occurring amines derived by enzymatic decarboxylation of the natural amino acids. Many have powerful physiological effects (e.g., histamine, serotonin, epinephrine, tyramine). Those derived from aromatic amino acids, and also their synthetic analogs (e.g., amphetamine), are of use in pharmacology.

Registry Number: 0

Descriptor UI: D001679

Alternative terms: Biogenic Amines; Biogenic Amine; Amine, Biogenic; Amines, Biogenic;

Related Mesh Headings: Receptors, Biogenic Amine;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists; biosynthesis; physiology;

Tree Number: D02.092.211;

History Note: 73(71)

Technical Notes: GEN or unspecified: prefer specific biogenic amine group term or specific biogenic amine indented under each

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