Biotin - Metabolism
Research News and Information

Sunday, November 22, 2009

Engineering monomeric streptavidin and its ligands with infinite affinity in binding but reversibility in interaction.

30 Oct 2009 Natural tetrameric streptavidin captures and immobilizes biotinylated molecules with ultra-tight binding (K(d) approximately 10(-13) to 10(-14) M). In contrast, engineered monomeric streptavidin offers reversible binding (K(d) approximately 10(-7) ... Read more...

Surface expression of sodium channels and transporters in rat kidney: effects of dietary sodium.

7 Sep 2009 The abundance of Na transport proteins in the luminal membrane of the rat kidney was assessed using in situ biotinylation and immunoblotting. When animals were fed an Na-deficient diet for 1 wk, the amounts of epithelial Na channel (ENaC) ... Read more...

Approach sensitivity in the retina processed by a multifunctional neural circuit.

4 Sep 2009 The detection of approaching objects, such as looming predators, is necessary for survival. Which neurons and circuits mediate this function? We combined genetic labeling of cell types, two-photon microscopy, electrophysiology and theoretical ... Read more...

Latest indexed articles for 'Biotin - Metabolism'

These are the very latest articles for this heading:

• Engineering monomeric streptavidin and its ligands with infinite affinity in binding but reversibility in interaction. 30 Oct 2009
• Surface expression of sodium channels and transporters in rat kidney: effects of dietary sodium. 7 Sep 2009
• Approach sensitivity in the retina processed by a multifunctional neural circuit. 4 Sep 2009
• Decreased renal perfusion rapidly increases plasma membrane Na-K-ATPase in rat cortex by an angiotensin II-dependent mechanism. 31 Aug 2009
• A case of renal osteodystrophy with unexpected serum intact parathyroid hormone concentrations. 30 Aug 2009
• The synthesis and characterization of biotin-silver-dendrimer nanocomposites as novel bioselective labels. 26 Aug 2009
• c-Src associates with ErbB2 through an interaction between catalytic domains and confers enhanced transforming potential. 22 Aug 2009
• Protein-ligand binding free energy calculation by the Smooth Reaction Path Generation (SRPG) Method. 30 Jul 2009
• A versatile targeting system with lentiviral vectors bearing the biotin-adaptor peptide. 30 Jul 2009
• Avidin fusion protein-expressing lentiviral vector for targeted drug delivery. 30 Jul 2009
• Biotinylated poly(amido)amine (PAMAM) dendrimers as carriers for drug delivery to ovarian cancer cells in vitro. 30 Jul 2009
• Quantum dots as new-generation fluorochromes for FISH: an appraisal. 29 Jul 2009
• The formation of acetylcholine receptor clusters visualized with quantum dots. 14 Jul 2009
• Translocation of a "winner" climbing fiber to the Purkinje cell dendrite and subsequent elimination of "losers" from the soma in developing cerebellum. 14 Jul 2009
• Protein folding roller coaster, one molecule at a time. 13 Jul 2009
• Impaired balance of mitochondrial fission and fusion in Alzheimer's disease. 13 Jul 2009
• Experimental determination of upper bound for transition path times in protein folding from single-molecule photon-by-photon trajectories. 5 Jul 2009
• A quantitative strategy to detect changes in accessibility of protein regions to chemical modification on heterodimerization. 29 Jun 2009
• Mrgprd enhances excitability in specific populations of cutaneous murine polymodal nociceptors. 29 Jun 2009
• Odor-evoked neural oscillations in Drosophila are mediated by widely branching interneurons. 29 Jun 2009

See a longer list of these articles.

Technical information about 'Biotin'

Definition: A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.

Chemical name: 1H-Thieno(3,4-d)imidazole-4-pentanoic acid, hexahydro-2-oxo-, (3aS-(3aalpha,4beta,6aalpha))-

Registry Number: 58-85-5

Descriptor UI: D001710

Alternative terms: Biotin; Vitamin H; H, Vitamin; Biokur; Biocur Brand of Biotin; Biotin Biocur Brand; Biotin Gelfert; Gelfert, Biotin; Ziethen Brand of Biotin; Biotin Ziethen Brand; Biotin Hermes; Hermes, Biotin; Hermes Brand of Biotin; Biotin Hermes Brand; Biotin-ratiopharm; Biotin ratiopharm; Biotinratiopharm; ratiopharm Brand of Biotin; Biotin ratiopharm Brand; Rombellin; Simons Brand of Biotin; Biotin Simons Brand; Biodermatin; e+b Pharma Brand of Biotin; Deacura; Dermapharm Brand of Biotin; Biotin Dermapharm Brand; Gabunat; Strathmann Brand of Biotin; Biotin Strathmann Brand; Medebiotin; Medea Brand of Biotin Sodium Salt; medobiotin; Medopharm Brand of Biotin; Biotin Medopharm Brand; Biotine Roche; Roche, Biotine; Roche Brand of Biotin; Biotin Roche Brand;

Related Mesh Headings: Avidin; Multiple Carboxylase Deficiency; Biotinidase Deficiency; Holocarboxylase Synthetase Deficiency;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Vitamin B Complex;

Tree Number: D03.383.129.308.080; D08.211.096;

Technical Notes: /ther use: coordinate disease with /drug ther, not /diet ther; deficiency: coordinate BIOTIN /defic (IM) with VITAMIN B DEFICIENCY (IM)