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Biphenyl Compounds
Research News and Information

Monday, November 23, 2009

Role of E166 in the imine to enamine tautomerization of the clinical beta-lactamase inhibitor sulbactam.

Nov 2009 Mechanism-based inhibitors of class A beta-lactamases, such as sulbactam, undergo a complex series of chemical reactions in the enzyme active site. Formation of a trans-enamine acyl-enzyme via a hydrolysis-prone imine is responsible for transient ... Read more...


An evaluation of extracts of five traditional medicinal plants from Iran on the inhibition of mushroom tyrosinase activity and scavenging of free radicals.

29 Sep 2009 This study aimed to evaluate the free radical scavenging and inhibition properties of five medicinal plants, including Quercus infectoria Olive., Terminalia chebula Retz., Lavendula stoechas L., Mentha longifolia L., Rheum palmatum L., toward the ... Read more...


Inhibitory effects of honokiol on LPS and PMA-induced cellular responses of macrophages and monocytes.

28 Sep 2009 The regulatory effects of honokiol on the cellular responses of macrophages and monocytes were evaluated. Specifically, we investigated the effects of honokiol with respect to lipopolysaccharide (LPS)-induced cytotoxicity, LPS- or ... Read more...

 

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Technical information about 'Biphenyl Compounds'

Registry Number: 0

Descriptor UI: D001713

Alternative terms: Biphenyl Compounds; Compounds, Biphenyl;

Allowable Qualifiers: metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists; administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification;

Tree Number: D02.455.426.559.389.185;

Technical Notes: DF: BIPHENYL CPDS

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