Blotting, Western
Research News and Information

Saturday, November 21, 2009

Protein kinase C alpha-dependent signaling mediates endometrial cancer cell growth and tumorigenesis.

29 Nov 2009 Endometrial cancer is the most common invasive gynecologic malignancy, yet molecular mechanisms and signaling pathways underlying its etiology and pathophysiology remain poorly characterized. We sought to define a functional role for the protein ... Read more...

Cell cycle-related kinase supports ovarian carcinoma cell proliferation via regulation of cyclin D1 and is a predictor of outcome in patients with ovarian carcinoma.

29 Nov 2009 Our previous study has suggested that the cell cycle-related kinase (CCRK) is a putative candidate oncogene in glioblastoma tumorigenesis. The potential oncogenic role of CCRK and its clinical/prognostic significance, however, in ovarian carcinoma ... Read more...

RhoB induces apoptosis via direct interaction with TNFAIP1 in HeLa cells.

29 Nov 2009 RhoB, a tumor suppressor, has emerged as an interesting cancer target, and extensive studies aimed at understanding its role in apoptosis have been performed. In our study, we investigated the involvement of RhoB-interacting molecules in apoptosis. ... Read more...

Latest indexed articles for 'Blotting, Western'

These are the very latest articles for this heading:

• Protein kinase C alpha-dependent signaling mediates endometrial cancer cell growth and tumorigenesis. 29 Nov 2009
• Cell cycle-related kinase supports ovarian carcinoma cell proliferation via regulation of cyclin D1 and is a predictor of outcome in patients with ovarian carcinoma. 29 Nov 2009
• RhoB induces apoptosis via direct interaction with TNFAIP1 in HeLa cells. 29 Nov 2009
• Prostaglandin E(2) promotes cell proliferation via protein kinase C/extracellular signal regulated kinase pathway-dependent induction of c-Myc expression in human esophageal squamous cell carcinoma cells. 29 Nov 2009
• Annexin-A7 protects normal prostate cells and induces distinct patterns of RB-associated cytotoxicity in androgen-sensitive and -resistant prostate cancer cells. 29 Nov 2009
• Downregulation of p21-activated kinase-1 inhibits the growth of gastric cancer cells involving cyclin B1. 29 Nov 2009
• Id-1 promotes tumorigenicity and metastasis of human esophageal cancer cells through activation of PI3K/AKT signaling pathway. 29 Nov 2009
• Antagonism of chemokine receptor CXCR3 inhibits osteosarcoma metastasis to lungs. 29 Nov 2009
• Overexpression of low-density lipoprotein receptor and lipid accumulation in intestinal polyps in Min mice. 29 Nov 2009
• Continuous and intermittent dosing of lonafarnib potentiates the therapeutic efficacy of docetaxel on preclinical human prostate cancer models. 29 Nov 2009
• HER3 is required for the maintenance of neuregulin-dependent and -independent attributes of malignant progression in prostate cancer cells. 29 Nov 2009
• Sphingosine kinase 1 inhibition sensitizes hormone-resistant prostate cancer to docetaxel. 29 Nov 2009
• Possible mechanisms involved in the discrepancy of hepatic and aortic endothelial nitric oxide synthases during the development of cirrhosis in rats. 25 Nov 2009
• The reduction of cell death and proliferation by p27(Kip1) minimizes DNA damage in an experimental model of genotoxicity. 13 Nov 2009
• Serum olfactomedin 4 (GW112, hGC-1) in combination with Reg IV is a highly sensitive biomarker for gastric cancer patients. 13 Nov 2009
• Chromosomal abnormalities and novel disease-related regions in progression from Barrett's esophagus to esophageal adenocarcinoma. 13 Nov 2009
• Fisetin, a natural flavonoid, targets chemoresistant human pancreatic cancer AsPC-1 cells through DR3-mediated inhibition of NF-kappaB. 13 Nov 2009
• Intrinsic resistance to the MEK1/2 inhibitor AZD6244 (ARRY-142886) is associated with weak ERK1/2 signalling and/or strong PI3K signalling in colorectal cancer cell lines. 13 Nov 2009
• Expression and role of adrenomedullin in renal tumors and value of its mRNA levels as prognostic factor in clear-cell renal carcinoma. 13 Nov 2009
• Enhanced expression of Annexin A4 in clear cell carcinoma of the ovary and its association with chemoresistance to carboplatin. 13 Nov 2009

See a longer list of these articles.

Technical information about 'Blotting, Western'

Definition: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.

Descriptor UI: D015153

Alternative terms: Blotting, Western; Blottings, Western; Western Blottings; Western Immunoblotting; Immunoblotting, Western; Immunoblottings, Western; Western Immunoblottings; Western Blotting; Blot, Western; Blots, Western; Western Blots; Immunoblot, Western; Immunoblots, Western; Western Immunoblots; Western Immunoblot; Western Blot;

Allowable Qualifiers: classification; economics; history; instrumentation; methods; standards; trends; utilization; veterinary; statistics & numerical data; ethics;

Tree Number: E01.450.495.410.320.100; E05.478.594.410.320.200; E05.601.155; E05.601.495.320.200;

History Note: 89

Technical Notes: "western" is not capitalized in titles or translations; DF: WESTERN BLOT