Bombesin - Research News and Information

Thursday, January 08, 2009

Bombesin-modified 6-14 C-terminal fragments adsorption on silver surfaces: influence of a surface substrate.

30 Oct 2008 Surface-enhanced Raman scattering (SERS) spectroscopy has been applied to investigate the interaction with a silver colloidal surface of following seven 6-14 fragments of bombesin (BN) C-terminus: cyclo[D-Phe(6),His(7),Leu(14)]BN(6-14), ... Read more...

Structural properties of bombesin-like peptides revealed by surface-enhanced Raman scattering on roughened silver electrodes.

30 Oct 2008 This work presents a Fourier-transform absorption infrared, Fourier-transform Raman, and surface-enhanced Raman scattering (SERS) study of the following peptides belonging to the bombesin-like family: phyllolitorin, [Leu(8)]phyllolitorin, NMB, NMC, ... Read more...

Surface-enhanced Raman difference between bombesin and its modified analogues on the colloidal and electrochemically roughen silver surfaces.

29 Sep 2008 In this article, surface-enhanced Raman scattering (SERS) spectra of bombesin (BN) and its six modified analogues ([D-Phe(12)]BN, [Tyr(4)]BN, [Tyr(4),D-Phe(12)]BN, [D-Phe(12),Leu(14)]BN, [Leu(13)-(R)-Leu(14)]BN, and [Lys(3)]BN) on a colloidal ... Read more...

Learn Faster Today      Improve your study skills

Latest indexed articles for 'Bombesin'

These are the very latest articles for this heading:

• Bombesin-modified 6-14 C-terminal fragments adsorption on silver surfaces: influence of a surface substrate. 30 Oct 2008
• Structural properties of bombesin-like peptides revealed by surface-enhanced Raman scattering on roughened silver electrodes. 30 Oct 2008
• Surface-enhanced Raman difference between bombesin and its modified analogues on the colloidal and electrochemically roughen silver surfaces. 29 Sep 2008
• Inhibitory effect of juniperonic acid (Delta-5c,11c,14c,17c-20:4, omega-3) on bombesin-induced proliferation of Swiss 3T3 cells. 30 Aug 2008
• Structures and bonding on a colloidal silver surface of the various length carboxyl terminal fragments of bombesin. 27 Aug 2008
• Targeted imaging of gastrin-releasing peptide receptors with 99mTc-EDDA/HYNIC-[Lys3]-bombesin: biokinetics and dosimetry in women. 30 Jul 2008
• Novel DOTA-based prochelator for divalent peptide vectorization: synthesis of dimeric bombesin analogues for multimodality tumor imaging and therapy. 18 Jun 2008
• Brain neuronal/inducible nitric oxide synthases and cyclooxygenase-1 are involved in the bombesin-induced activation of central adrenomedullary outflow in rats. 16 Jun 2008
• Pleiotropic effects of bombesin and neurotensin on intestinal mucosa: not just trefoil peptides. 12 Jun 2008
• Investigation of molecular structure of bombesin and its modified analogues nonadsorbed and adsorbed on electrochemically roughened silver surface. 30 May 2008
• 99mTc-labeled bombesin(7-14)NH2 with favorable properties for SPECT imaging of colon cancer. 19 May 2008
• Sexually dimorphic gastrin releasing peptide system in the spinal cord controls male reproductive functions. 16 May 2008
• Radiolabeled bombesin analogs for prostate cancer diagnosis: preclinical studies. 29 Apr 2008
• Observations favouring the occurrence of local production and marked effects of bombesin/gastrin-releasing peptide in the synovial tissue of the human knee joint--comparisons with substance P and the NK-1 receptor. 30 Mar 2008
• 99mTc(CO)3-DTMA bombesin conjugates having high affinity for the GRP receptor. 30 Mar 2008
• Therapy of experimental hepatic cancers with cytotoxic peptide analogs targeted to receptors for luteinizing hormone-releasing hormone, somatostatin or bombesin. 30 Mar 2008
• Bombesin: a possible role in wound repair. 12 Mar 2008
• Release of neuroendocrine products in the pulmonary circulation during intermittent hypoxia in isolated rat lung. 10 Mar 2008
• The impact of diet and micronutrient supplements on the expression of neuroendocrine markers in murine Lady transgenic prostate. 28 Feb 2008
• A novel vaccine targeting gastrin-releasing peptide: efficient inhibition of breast cancer growth in vivo. 28 Feb 2008

See a longer list of these articles.

Technical information about 'Bombesin'

Definition: A tetradecapeptide originally obtained from the skins of toads Bombina bombina and B. variegata. It is also an endogenous neurotransmitter in many animals including mammals. Bombesin affects vascular and other smooth muscle, gastric secretion, and renal circulation and function.

Chemical name: 5-oxoPro-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-MetNH2

Registry Number: 31362-50-2

Descriptor UI: D001839

Alternative terms: Bombesin; Bombesin 14; Bombesin Dihydrochloride; Dihydrochloride, Bombesin;

Related Mesh Headings: Receptors, Bombesin;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Neurotransmitter Agents;

Tree Number: D06.472.699.100; D12.644.400.085; D12.644.548.100; D12.776.641.650.085; D20.888.033.137; D23.946.833.033.137;

History Note: 86(75); was see under PEPTIDES 1975-85