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Bone and Bones - Cytology
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Definition of 'Bone and Bones'

A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principle cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.

Common names: Bone and Bones; Bones and Bone; Bones and Bone Tissue; Bones; Bone Tissue; Bone Tissues; Tissue, Bone; Tissues, Bone; Bone

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Monday, November 23, 2009

Direct effects of osteoprotegerin on human bone cell metabolism.

9 Sep 2009 PURPOSE: Osteoprotegerin (OPG) affects bone metabolism by intercepting the RANK-RANKL interaction which prevents osteoclastic differentiation and consequently reduces bone resorption. Different bone phenotypes of mice overexpressing OPG and of mice ... Read more...


The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo.

Sep 2009 GPR55 is a G protein-coupled receptor recently shown to be activated by certain cannabinoids and by lysophosphatidylinositol (LPI). However, the physiological role of GPR55 remains unknown. Given the recent finding that the cannabinoid receptors ... Read more...


Autoradiographic studies of rhenium-188-hydroxyethylidine diphosphonate in normal skeleton and osteoblastic bone metastases in a rat model of metastatic prostate cancer.

30 Aug 2009 AIM: The quantitative distribution of bone-seeking radiopharmaceuticals in trabecular bone, cortical bone and in skeletal metastases is required for calculation of radiation-absorbed dose in radionuclide therapy. An animal model of intraosseous ... Read more...

 

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Technical information about 'Bone and Bones'

Definition: A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principle cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.

Descriptor UI: D001842

Alternative terms: Bone and Bones; Bones and Bone; Bones and Bone Tissue; Bones; Bone Tissue; Bone Tissues; Tissue, Bone; Tissues, Bone; Bone;

Related Mesh Headings: Arthrodesis; Calcification, Physiologic; Osteogenesis; Osteotomy;

Allowable Qualifiers: abnormalities; anatomy & histology; blood supply; cytology; drug effects; embryology; enzymology; immunology; injuries; innervation; metabolism; microbiology; parasitology; pathology; physiology; physiopathology; radiation effects; radiography; radionuclide imaging; surgery; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A02.835.232; A10.165.265;

Online Note: use BONE TRANSPLANTATION to search BONE AND BONES/transplantation 1966-89

History Note: /transplantation was BONE TRANSPLANTATION 1963-65; was BONE AND BONES/transplantation 1966-89

Technical Notes: /cytol: consider also OSTEOBLASTS; OSTEOCLASTS; OSTEOCYTES; /embryol: consider also OSTEOGENESIS; /surg: consider also OSTEOTOMY or ARTHRODESIS or FRACTURE FIXATION & its specifics; osteosynthesis not one of the preceding terms goes under BONE AND BONES /surg; differentiate from SKELETON which is almost never used: restrict SKELETON to bone arrangement as a whole & not for "skeletal" which usually means "bone" ( = BONE AND BONES); "disappearing bone" = OSTEOLYSIS, ESSENTIAL; inflammation = OSTEITIS; necrosis = OSTEONECROSIS; "bone minerals" = BONE AND BONES (IM) + MINERALS (IM) or specific mineral (IM)

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