Bone and Bones - Drug effects
Research News and Information

Sunday, November 22, 2009

CCL20/CCR6 chemokine/receptor expression in bone tissue from osteoarthritis and rheumatoid arthritis patients: different response of osteoblasts in the two groups.

29 Sep 2009 Subchondral bone remodeling in osteoarthritis (OA) and rheumatoid arthritis (RA) is mainly characterized by the formation of osteophytes/fibrosis and by the presence of infiltrating cells associated to bone resorption. In this study we analyzed CC ... Read more...

Inhibition of glycogen synthase kinase-3beta attenuates glucocorticoid-induced bone loss.

23 Sep 2009 AIMS: Long-term glucocorticoid administration is known to induce bone deterioration. Glycogen synthase kinase-3beta (GSK-3beta) signaling reportedly participates in bone remodeling. This study investigated whether GSK-3beta inhibitor could regulate ... Read more...

Direct effects of osteoprotegerin on human bone cell metabolism.

9 Sep 2009 PURPOSE: Osteoprotegerin (OPG) affects bone metabolism by intercepting the RANK-RANKL interaction which prevents osteoclastic differentiation and consequently reduces bone resorption. Different bone phenotypes of mice overexpressing OPG and of mice ... Read more...

Latest indexed articles for 'Bone and Bones - Drug effects'

These are the very latest articles for this heading:

• CCL20/CCR6 chemokine/receptor expression in bone tissue from osteoarthritis and rheumatoid arthritis patients: different response of osteoblasts in the two groups. 29 Sep 2009
• Inhibition of glycogen synthase kinase-3beta attenuates glucocorticoid-induced bone loss. 23 Sep 2009
• Direct effects of osteoprotegerin on human bone cell metabolism. 9 Sep 2009
• Exposure to cadmium and persistent organochlorine pollutants and its association with bone mineral density and markers of bone metabolism on postmenopausal women. 3 Sep 2009
• The impact of human superoxide dismutase 1 expression in a mouse model on the embryotoxicity of hydroxyurea. 30 Aug 2009
• Cytocompatibility of a free machining titanium alloy containing lanthanum. 30 Aug 2009
• Biocompatibility and mesenchymal stem cell response to poly(epsilon-caprolactone) nanowire surfaces for orthopedic tissue engineering. 30 Aug 2009
• Umbilical cord Wharton's Jelly: a new potential cell source of mesenchymal stromal cells for bone tissue engineering. 30 Aug 2009
• Blocking of CD27-CD70 pathway by anti-CD70 antibody ameliorates joint disease in murine collagen-induced arthritis. 24 Aug 2009
• Dose-response relationships of rat fetal skeleton variations: Relevance for risk assessment. 11 Aug 2009
• Increased lipid oxidation causes oxidative stress, increased peroxisome proliferator-activated receptor-gamma expression, and diminished pro-osteogenic Wnt signaling in the skeleton. 3 Aug 2009
• Pilot study of targeted skeletal radiation therapy for bone-only metastatic breast cancer. 30 Jul 2009
• Comparative effects of teriparatide and strontium ranelate on bone biopsies and biochemical markers of bone turnover in postmenopausal women with osteoporosis. 30 Jul 2009
• Heavy heart, thin bones? The evidence suggests that selective serotonin reuptake inhibitors may erode bone. 30 Jul 2009
• Corticosteroids: no drug prevention of fractures needed. 30 Jul 2009
• Bone disease induced by phenytoin therapy: clinical and experimental study. 21 Jul 2009
• Phytoestrogen modulation of bone-related cytokines and its impact on cell viability in human prostate cancer cells. 21 Jul 2009
• Does exercise modify the effects of zoledronic acid on bone mass, microarchitecture, biomechanics, and turnover in ovariectomized rats? 15 Jul 2009
• Changes in bone mineral density 10 years after marked reduction of cadmium exposure in a Chinese population. 15 Jul 2009
• A comparison of glycemic control, water retention, and musculoskeletal effects of balaglitazone and pioglitazone in diet-induced obese rats. 8 Jul 2009

See a longer list of these articles.

Technical information about 'Bone and Bones'

Definition: A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principle cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.

Descriptor UI: D001842

Alternative terms: Bone and Bones; Bones and Bone; Bones and Bone Tissue; Bones; Bone Tissue; Bone Tissues; Tissue, Bone; Tissues, Bone; Bone;

Related Mesh Headings: Arthrodesis; Calcification, Physiologic; Osteogenesis; Osteotomy;

Allowable Qualifiers: abnormalities; anatomy & histology; blood supply; cytology; drug effects; embryology; enzymology; immunology; injuries; innervation; metabolism; microbiology; parasitology; pathology; physiology; physiopathology; radiation effects; radiography; radionuclide imaging; surgery; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A02.835.232; A10.165.265;

Online Note: use BONE TRANSPLANTATION to search BONE AND BONES/transplantation 1966-89

History Note: /transplantation was BONE TRANSPLANTATION 1963-65; was BONE AND BONES/transplantation 1966-89

Technical Notes: /cytol: consider also OSTEOBLASTS; OSTEOCLASTS; OSTEOCYTES; /embryol: consider also OSTEOGENESIS; /surg: consider also OSTEOTOMY or ARTHRODESIS or FRACTURE FIXATION & its specifics; osteosynthesis not one of the preceding terms goes under BONE AND BONES /surg; differentiate from SKELETON which is almost never used: restrict SKELETON to bone arrangement as a whole & not for "skeletal" which usually means "bone" ( = BONE AND BONES); "disappearing bone" = OSTEOLYSIS, ESSENTIAL; inflammation = OSTEITIS; necrosis = OSTEONECROSIS; "bone minerals" = BONE AND BONES (IM) + MINERALS (IM) or specific mineral (IM)