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Bone Morphogenetic Proteins
Research News and Information
Definition of 'Bone Morphogenetic Proteins'Bone-growth regulatory factors that are members of the transforming growth factor-beta superfamily of proteins. They are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. The active form can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins. Common names: Bone Morphogenetic Proteins; Morphogenetic Proteins, Bone; Bone Morphogenetic Protein; Morphogenetic Protein, Bone |
Sunday, November 22, 2009
30 Oct 2009
Neural stem cells (NSCs) are a promising source for cell replacement therapies for neurological diseases. Administration of NSCs into the cerebrospinal fluid (CSF) offers a nontraumatic transplantation method into the brain. However, cell survival ... Read more...
10 Oct 2009
Patients with classic fibrodysplasia ossificans progressiva, a disorder characterized by extensive extraskeletal endochondral bone formation, share a recurrent mutation (R206H) within the glycine/serine-rich domain of ACVR1/ALK2, a bone ... Read more...
5 Oct 2009
Cone photopigments, known as opsins, are pivotal elements and the first detection module used in color vision. In mice, cone photoreceptors are distributed throughout the retina, and short-wavelength (S) and medium-wavelength (M) opsins have unique ... Read more...
Latest indexed articles for 'Bone Morphogenetic Proteins'
These are the very latest articles for this heading:
- Adult cerebrospinal fluid inhibits neurogenesis but facilitates gliogenesis from fetal rat neural stem cells.
30 Oct 2009 - The fibrodysplasia ossificans progressiva R206H ACVR1 mutation activates BMP-independent chondrogenesis and zebrafish embryo ventralization.
10 Oct 2009 - The spatial patterning of mouse cone opsin expression is regulated by bone morphogenetic protein signaling through downstream effector COUP-TF nuclear receptors.
5 Oct 2009 - Mixing conditions for cell scaffolds affect the bone formation induced by bone engineering with human bone marrow stromal cells, beta-tricalcium phosphate granules, and rhBMP-2.
29 Sep 2009 - The glypican Dally is required in the niche for the maintenance of germline stem cells and short-range BMP signaling in the Drosophila ovary.
28 Sep 2009 - BMP signaling regulates sympathetic nervous system development through Smad4-dependent and -independent pathways.
28 Sep 2009 - BMP inhibition initiates neural induction via FGF signaling and Zic genes.
26 Sep 2009 - [Army doctor accused of falsifying data]
22 Sep 2009 - Pathways to embryonic heart failure.
16 Sep 2009 - Long adult spinal deformity fusion to the sacrum using rhBMP-2 versus autogenous iliac crest bone graft.
13 Sep 2009 - Receptor oligomerization and beyond: a case study in bone morphogenetic proteins.
5 Sep 2009 - Scaling of BMP gradients in Xenopus embryos.
Sep 2009 - Pretreatment of distraction docking sites with bone morphogenetic protein (rhBMP-2).
30 Aug 2009 - Pivotal, randomized, parallel evaluation of recombinant human bone morphogenetic protein-2/absorbable collagen sponge and autogenous bone graft for maxillary sinus floor augmentation.
30 Aug 2009 - Outflow tract cushions perform a critical valve-like function in the early embryonic heart requiring BMPRIA-mediated signaling in cardiac neural crest.
26 Aug 2009 - Look who's talking: FGFs and BMPs in the proepicardium.
26 Aug 2009 - Disruption of Smad4 in odontoblasts causes multiple keratocystic odontogenic tumors and tooth malformation in mice.
22 Aug 2009 - [Autologous bone or bone substitutes in spinal fusion]
17 Aug 2009 - Phosphorylation dynamics during early differentiation of human embryonic stem cells.
5 Aug 2009 - Tbx20 interacts with smads to confine tbx2 expression to the atrioventricular canal.
4 Aug 2009
See a longer list of these articles.
Technical information about 'Bone Morphogenetic Proteins'
Definition: Bone-growth regulatory factors that are members of the transforming growth factor-beta superfamily of proteins. They are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. The active form can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins.
Registry Number: 0
Descriptor UI: D019485
Alternative terms: Bone Morphogenetic Proteins; Morphogenetic Proteins, Bone; Bone Morphogenetic Protein; Morphogenetic Protein, Bone;
Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;
Tree Number: D12.644.276.954.200; D12.776.467.942.200; D23.529.942.200;
Online Note: use BONE MORPHOGENETIC PROTEINS (NM) to search BONE MORPHOGENETIC PROTEIN 1981-96
History Note: 97; was BONE MORPHOGENETIC PROTEIN (NM) 1981-96
Technical Notes: general; prefer specifics