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Brain - Cytology
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Definition of 'Brain'

The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.

Common names: Brain; Brains; Encephalon; Encephalons

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Saturday, November 21, 2009

Rab22B is expressed in the CNS astroglia lineage and plays a role in epidermal growth factor receptor trafficking in A431 cells.

29 Nov 2009 The expression profile and functions of the brain-enriched Rab22B/Rab31 small GTPase had remained uncharacterized. Using specific antibodies against Rab22B, we found the protein to be exceptionally enriched in nestin and RC2-positive radial glia of ... Read more...


Temperature entrainment of Drosophila's circadian clock involves the gene nocte and signaling from peripheral sensory tissues to the brain.

27 Oct 2009 Circadian clocks are synchronized by the natural day/night and temperature cycles. Our previous work demonstrated that synchronization by temperature is a tissue autonomous process, similar to synchronization by light. We show here that this is ... Read more...


SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice.

27 Oct 2009 Nuclear movement is critical during neurogenesis and neuronal migration, which are fundamental for mammalian brain development. Although dynein, Lis1, and other cytoplasmic proteins are known for their roles in connecting microtubules to the nucleus ... Read more...

 

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Technical information about 'Brain'

Definition: The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.

Descriptor UI: D001921

Alternative terms: Brain; Brains; Encephalon; Encephalons;

Related Mesh Headings: Cerebral Decortication; Psychosurgery;

Allowable Qualifiers: abnormalities; anatomy & histology; blood supply; cytology; drug effects; embryology; enzymology; growth & development; immunology; metabolism; microbiology; parasitology; pathology; physiology; physiopathology; radiation effects; radiography; radionuclide imaging; secretion; surgery; ultrastructure; virology;

Tree Number: A08.186.211;

Online Note: pre-explosion = BRAIN (PX)

History Note: /enzymology was BRAIN ENZYMOLOGY 1964-65; /physiology was BRAIN PHYSIOLOGY 1965; BRAIN ELECTROPHYSIOLOGY was heading 1964-65

Technical Notes: general; /blood supply: consider also CEREBROVASCULAR CIRCULATION; CEREBRAL ARTERIES; CEREBRAL VEINS; CRANIAL SINUSES; /cytol: do not routinely convert to NEURONS; /surg: consider specific neurosurgical procedures in Category E4; inflammation = ENCEPHALITIS & its specifics; infarct = CEREBRAL INFARCTION; malacia = ENCEPHALOMALACIA; brain-isolated, encéphale isolé, cerveau isolé: index DECEREBRATE STATE

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