Brain Chemistry - Drug effects
Research News and Information

Saturday, November 21, 2009

Decreased brain edema after collagenase-induced intracerebral hemorrhage in mice lacking the inducible nitric oxide synthase gene. Laboratory investigation.

30 Oct 2009 OBJECT: Hematoma size and brain edema after intracerebral hemorrhage (ICH) are important prognostic factors. Inducible nitric oxide synthase (iNOS) is induced after cerebral ischemia and is known to be involved in secondary neuronal injury, but its ... Read more...

A neurocomputational model for cocaine addiction.

29 Sep 2009 Based on the dopamine hypotheses of cocaine addiction and the assumption of decrement of brain reward system sensitivity after long-term drug exposure, we propose a computational model for cocaine addiction. Utilizing average reward temporal ... Read more...

What has positron emission tomography told us about the epileptogenic zone?

6 Sep 2009 There is no one ligand for visualising "the epileptogenic zone". Several PET ligands, however, can help by noninvasively or minimally invasively refining hypotheses regarding its location. Their relative merits depend not only on local availability ... Read more...

Latest indexed articles for 'Brain Chemistry - Drug effects'

These are the very latest articles for this heading:

• Decreased brain edema after collagenase-induced intracerebral hemorrhage in mice lacking the inducible nitric oxide synthase gene. Laboratory investigation. 30 Oct 2009
• A neurocomputational model for cocaine addiction. 29 Sep 2009
• What has positron emission tomography told us about the epileptogenic zone? 6 Sep 2009
• Tetrahydrobiopterin in the prevention of hypertonia in hypoxic fetal brain. 30 Aug 2009
• Laterality of cortical response to ethanol is moderated by TaqIA A1 allele. 30 Aug 2009
• [(3)H]4-(Dimethylamino)-N-[4-(4-(2-methoxyphenyl)piperazin- 1-yl)butyl]benzamide, a selective radioligand for dopamine D(3) receptors. I. In vitro characterization. 30 Aug 2009
• Lithium-induced enhancement of mitochondrial oxidative phosphorylation in human brain tissue. 30 Jul 2009
• Involvement of extracellular ascorbate and iron in hydroxyl radical generation in rat striatum in carbon monoxide poisoning. 22 Jul 2009
• CNS penetration of small molecules following local inflammation, widespread systemic inflammation or direct injury to the nervous system. 22 Jul 2009
• Coordinated regulation of angiopoietin-1 and vascular endothelial growth factor by arsenite in human brain microvascular pericytes: implications of arsenite-induced vascular dysfunction. 17 Jul 2009
• Long-term melatonin administration protects brain mitochondria from aging. 29 Jun 2009
• [Comparison of the effects of selank and tuftsin on the metabolism of serotonin in the brain of rats pretreated with PCPA] 29 Jun 2009
• Aldehyde fixative solutions alter the water relaxation and diffusion properties of nervous tissue. 29 Jun 2009
• Dimebolin is a 5-HT6 antagonist with acute cognition enhancing activities. 19 Jun 2009
• Minocycline attenuates oxidative/nitrosative stress and cerebral complications of acute liver failure in rats. 9 Jun 2009
• Memantine: a new hope for treatment of Lewy body-related dementias? 8 Jun 2009
• High precision liquid chromatography analysis of dopaminergic and serotoninergic responses to acute alcohol exposure in zebrafish. 6 Jun 2009
• ERK phosphorylation in intact, adult brain by alpha(2)-adrenergic transactivation of EGF receptors. 4 Jun 2009
• Neuroprotective role of Convolvulus pluricaulis on aluminium induced neurotoxicity in rat brain. 4 Jun 2009
• Improving antidepressant drugs: update on recently patented compounds. 30 May 2009

See a longer list of these articles.

Technical information about 'Brain Chemistry'

Definition: Changes in the amounts of various chemicals (neurotransmitters, receptors, enzymes, and other metabolites) specific to the area of the central nervous system contained within the head. These are monitored over time, during sensory stimulation, or under different disease states.

Descriptor UI: D001923

Alternative terms: Brain Chemistry; Chemistry, Brain; Brain Chemistries; Chemistries, Brain;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects;

Tree Number: G02.111.100; G03.200;

History Note: 65

Technical Notes: differentiate from BRAIN /metab; consider also /chem with specific parts of the brain but probably as NIM with BRAIN CHEMISTRY (IM) if site is merely locational & illustrative