Brain Chemistry
Research News and Information

Saturday, November 07, 2009

Genetic complexity of absence seizures in substrains of C3H mice.

15 Dec 2009 Absence epilepsy is a common form of idiopathic generalized epilepsy whose etiology is poorly understood because of genetic and phenotypic heterogeneity. The inbred mouse strain C3H/He exhibits spontaneous absence seizures characterized by spike and ... Read more...

The potassium channel subunit Kvbeta3 interacts with pannexin 1 and attenuates its sensitivity to changes in redox potentials.

22 Sep 2009 Pannexin 1 (Panx1), a member of the second gap junction protein family identified in vertebrates, appears to preferentially form non-junctional membrane channels. A candidate regulatory protein of Panx1 is the potassium channel subunit Kvbeta3, ... Read more...

Tetrahydrobiopterin in the prevention of hypertonia in hypoxic fetal brain.

30 Aug 2009 OBJECTIVE: Tetrahydrobiopterin (BH(4)) deficiency is a cause of dystonia at birth. We hypothesized that BH(4) is a developmental factor determining vulnerability of the immature fetal brain to hypoxic-ischemic injury and subsequent motor deficits in ... Read more...

Latest indexed articles for 'Brain Chemistry'

These are the very latest articles for this heading:

• Genetic complexity of absence seizures in substrains of C3H mice. 15 Dec 2009
• Alzheimer's biomarker initiative hits its stride. 14 Oct 2009
• The potassium channel subunit Kvbeta3 interacts with pannexin 1 and attenuates its sensitivity to changes in redox potentials. 22 Sep 2009
• Tetrahydrobiopterin in the prevention of hypertonia in hypoxic fetal brain. 30 Aug 2009
• Choroid plexus connexin 43 expression and gap junction flexibility are associated with clinical features of acute EAE. 30 Aug 2009
• Isolation and biochemical characterization of amyloid plaques and paired helical filaments. 30 Aug 2009
• Disparate diseases due to copycat copy number variations. 30 Aug 2009
• Field-free transmission geometry atmospheric pressure matrix-assisted laser desorption/ionization for rapid analysis of unadulterated tissue samples. 30 Aug 2009
• Development of oligomeric prion-protein aggregates in a mouse model of prion disease. 30 Aug 2009
• Laterality of cortical response to ethanol is moderated by TaqIA A1 allele. 30 Aug 2009
• [(3)H]4-(Dimethylamino)-N-[4-(4-(2-methoxyphenyl)piperazin- 1-yl)butyl]benzamide, a selective radioligand for dopamine D(3) receptors. I. In vitro characterization. 30 Aug 2009
• Physical activity: one of the easiest ways to protect the brain? 30 Aug 2009
• Prolonged intake of coenzyme Q10 impairs cognitive functions in mice. 24 Aug 2009
• TRIL, a functional component of the TLR4 signaling complex, highly expressed in brain. 24 Aug 2009
• GATA factors in human neuroblastoma: distinctive expression patterns in clinical subtypes. 23 Aug 2009
• Synaptotagmin-mediated bending of the target membrane is a critical step in Ca(2+)-regulated fusion. 19 Aug 2009
• Autocrine semaphorin 3A signaling promotes glioblastoma dispersal. 15 Aug 2009
• Neuropathology. A late hit for pro football players. 5 Aug 2009
• Obtaining high quality RNA from single cell populations in human postmortem brain tissue. 4 Aug 2009
• Journal club. A systems biologist ponders how disparate ideas can sometimes come together beautifully. 4 Aug 2009

See a longer list of these articles.

Technical information about 'Brain Chemistry'

Definition: Changes in the amounts of various chemicals (neurotransmitters, receptors, enzymes, and other metabolites) specific to the area of the central nervous system contained within the head. These are monitored over time, during sensory stimulation, or under different disease states.

Descriptor UI: D001923

Alternative terms: Brain Chemistry; Chemistry, Brain; Brain Chemistries; Chemistries, Brain;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects;

Tree Number: G02.111.100; G03.200;

History Note: 65

Technical Notes: differentiate from BRAIN /metab; consider also /chem with specific parts of the brain but probably as NIM with BRAIN CHEMISTRY (IM) if site is merely locational & illustrative