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Brain Ischemia
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Definition of 'Brain Ischemia'

Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.

Common names: Brain Ischemia; Brain Ischemias; Ischemia, Brain; Ischemic Encephalopathy; Encephalopathy, Ischemic; Ischemic Encephalopathies; Cerebral Ischemia; Cerebral Ischemias; Ischemias, Cerebral; Ischemia, Cerebral

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Sunday, November 22, 2009

Estrogen attenuates ischemic oxidative damage via an estrogen receptor alpha-mediated inhibition of NADPH oxidase activation.

2 Nov 2009 The goal of this study was to elucidate the mechanisms of 17beta-estradiol (E(2)) antioxidant and neuroprotective actions in stroke. The results reveal a novel extranuclear receptor-mediated antioxidant mechanism for E(2) during stroke, as well as a ... Read more...


A nanomedicine transports a peptide caspase-3 inhibitor across the blood-brain barrier and provides neuroprotection.

2 Nov 2009 Caspases play an important role as mediators of cell death in acute and chronic neurological disorders. Although peptide inhibitors of caspases provide neuroprotection, they have to be administered intracerebroventricularly because they cannot cross ... Read more...


Edema formation in the hyperacute phase of ischemic stroke. Laboratory investigation.

30 Oct 2009 OBJECT: Brain edema formation is a serious complication of ischemic stroke and can lead to mechanical compression of adjacent brain structures, cerebral herniation, and death. Furthermore, the space-occupying effect of edema impairs regional ... Read more...

 

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Technical information about 'Brain Ischemia'

Definition: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.

Descriptor UI: D002545

Alternative terms: Brain Ischemia; Brain Ischemias; Ischemia, Brain; Ischemic Encephalopathy; Encephalopathy, Ischemic; Ischemic Encephalopathies; Cerebral Ischemia; Cerebral Ischemias; Ischemias, Cerebral; Ischemia, Cerebral;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C10.228.140.300.150; C14.907.253.092;

History Note: 2000(1979)

Technical Notes: ISCHEMIC ATTACK, TRANSIENT is available

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