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Brain
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Definition of 'Brain'

The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.

Common names: Brain; Brains; Encephalon; Encephalons

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Friday, November 20, 2009

Biomarkers in the cerebrospinal fluid and neurodegeneration in Langerhans cell histiocytosis.

13 Dec 2009 BACKGROUND: Progressive neurodegeneration may result in potentially severe cognitive and motor dysfunctions as a complication of Langerhans cell histiocytosis (LCH), a suggested IL-17A-associated inflammatory condition. To detect this complication ... Read more...


Rab22B is expressed in the CNS astroglia lineage and plays a role in epidermal growth factor receptor trafficking in A431 cells.

29 Nov 2009 The expression profile and functions of the brain-enriched Rab22B/Rab31 small GTPase had remained uncharacterized. Using specific antibodies against Rab22B, we found the protein to be exceptionally enriched in nestin and RC2-positive radial glia of ... Read more...


Bevacizumab as therapy for radiation necrosis in four children with pontine gliomas.

13 Nov 2009 PURPOSE: Diffuse pontine gliomas are a pediatric brain tumor that is fatal in nearly all patients. Given the poor prognosis for patients with this tumor, their quality of life is very important. Radiation therapy provides some palliation, but can ... Read more...

 

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Technical information about 'Brain'

Definition: The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.

Descriptor UI: D001921

Alternative terms: Brain; Brains; Encephalon; Encephalons;

Related Mesh Headings: Cerebral Decortication; Psychosurgery;

Allowable Qualifiers: abnormalities; anatomy & histology; blood supply; cytology; drug effects; embryology; enzymology; growth & development; immunology; metabolism; microbiology; parasitology; pathology; physiology; physiopathology; radiation effects; radiography; radionuclide imaging; secretion; surgery; ultrastructure; virology;

Tree Number: A08.186.211;

Online Note: pre-explosion = BRAIN (PX)

History Note: /enzymology was BRAIN ENZYMOLOGY 1964-65; /physiology was BRAIN PHYSIOLOGY 1965; BRAIN ELECTROPHYSIOLOGY was heading 1964-65

Technical Notes: general; /blood supply: consider also CEREBROVASCULAR CIRCULATION; CEREBRAL ARTERIES; CEREBRAL VEINS; CRANIAL SINUSES; /cytol: do not routinely convert to NEURONS; /surg: consider specific neurosurgical procedures in Category E4; inflammation = ENCEPHALITIS & its specifics; infarct = CEREBRAL INFARCTION; malacia = ENCEPHALOMALACIA; brain-isolated, encéphale isolé, cerveau isolé: index DECEREBRATE STATE

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