Breast Neoplasms - Immunology
Research News and Information

Sunday, November 22, 2009

Gene expression profiling integrated into network modelling reveals heterogeneity in the mechanisms of BRCA1 tumorigenesis.

18 Oct 2009 BACKGROUND: Gene expression profiling has distinguished sporadic breast tumour classes with genetic and clinical differences. Less is known about the molecular classification of familial breast tumours, which are generally considered to be less ... Read more...

Molecular evolution of specific human antibody against MUC1 mucin results in improved recognition of the antigen on tumor cells.

19 Sep 2009 The MUC1 mucin is differentially expressed and glycosylated in cancer tissue as opposed to healthy tissue. Due to these differences, MUC1 is considered a potential biomarker suitable for cancer diagnosis and therapy. In a previous study, the human ... Read more...

Phosphorothioate-modified TLR9 ligands protect cancer cells against TRAIL-induced apoptosis.

2 Sep 2009 Hypomethylated CpG oligodeoxynucleotides (CpG ODNs) target TLR9 expressed by immune cells and are currently being evaluated as adjuvants in clinical trials. However, TLR signaling can promote some tumor growth and immune evasion, such as in multiple ... Read more...

Latest indexed articles for 'Breast Neoplasms - Immunology'

These are the very latest articles for this heading:

• Gene expression profiling integrated into network modelling reveals heterogeneity in the mechanisms of BRCA1 tumorigenesis. 18 Oct 2009
• Molecular evolution of specific human antibody against MUC1 mucin results in improved recognition of the antigen on tumor cells. 19 Sep 2009
• Phosphorothioate-modified TLR9 ligands protect cancer cells against TRAIL-induced apoptosis. 2 Sep 2009
• Clinical use of anti-CD25 antibody daclizumab to enhance immune responses to tumor antigen vaccination by targeting regulatory T cells. 30 Aug 2009
• Combining conventional therapies with intratumoral injection of autologous dendritic cells and activated T cells to treat patients with advanced cancers. 30 Aug 2009
• Parathyroid hormone-related protein protects against mammary tumor emergence and is associated with monocyte infiltration in ductal carcinoma in situ. 30 Aug 2009
• Metastasis: Influencing bad behaviour. 30 Aug 2009
• Effective anti-tumor responses induced by recombinant bacillus Calmette-Guérin vaccines based on different tandem repeats of MUC1 and GM-CSF. 30 Aug 2009
• A comparison of estrogen receptor SP1 and 1D5 monoclonal antibodies in routine clinical use reveals similar staining results. 30 Aug 2009
• Concurrent trastuzumab and HER2/neu-specific vaccination in patients with metastatic breast cancer. 29 Aug 2009
• A low number of tumor-infiltrating FOXP3-positive cells during primary systemic chemotherapy correlates with favorable anti-tumor response in patients with breast cancer. 30 Jul 2009
• Fever and dyspnea in a 61-year-old woman with metastatic breast cancer. 30 Jul 2009
• CT-X antigen expression in human breast cancer. 25 Jul 2009
• Autophagy facilitates the development of breast cancer resistance to the anti-HER2 monoclonal antibody trastuzumab. 14 Jul 2009
• Proteomic identification of an MHC-binding peptidome from pancreas and breast cancer cell lines. 14 Jul 2009
• Increased frequency of nonconventional double positive CD4CD8 alphabeta T cells in human breast pleural effusions. 13 Jul 2009
• From synthesis to biologics: preclinical data on a chemistry derived anticancer vaccine. 6 Jul 2009
• Identification of a new panel of serum autoantibodies associated with the presence of in situ carcinoma of the breast in younger women. 5 Jul 2009
• Honokiol-mediated inhibition of PI3K/mTOR pathway: a potential strategy to overcome immunoresistance in glioma, breast, and prostate carcinoma without impacting T cell function. 29 Jun 2009
• Dual potency anti-HER2/neu and anti-EGFR anthracycline immunoconjugates in chemotherapeutic-resistant mammary carcinoma combined with cyclosporin A and verapamil P-glycoprotein inhibition. 29 Jun 2009

See a longer list of these articles.

Technical information about 'Breast Neoplasms'

Definition: Tumors or cancer of the human BREAST.

Descriptor UI: D001943

Alternative terms: Breast Neoplasms; Breast Neoplasm; Neoplasm, Breast; Neoplasms, Breast; Tumors, Breast; Breast Tumors; Breast Tumor; Tumor, Breast; Mammary Carcinoma, Human; Carcinoma, Human Mammary; Carcinomas, Human Mammary; Human Mammary Carcinomas; Mammary Carcinomas, Human; Human Mammary Carcinoma; Mammary Neoplasms, Human; Human Mammary Neoplasm; Human Mammary Neoplasms; Neoplasm, Human Mammary; Neoplasms, Human Mammary; Mammary Neoplasm, Human; Breast Cancer; Cancer, Breast; Cancer of the Breast; Cancer of Breast;

Allowable Qualifiers: blood; blood supply; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; secondary; secretion; surgery; therapy; ultrastructure; urine; veterinary; ultrasonography; chemistry; virology;

Tree Number: C04.588.180; C17.800.090.500;

Technical Notes: human only; BREAST NEOPLASMS, MALE is also available; for animal use MAMMARY NEOPLASMS, ANIMAL or MAMMARY NEOPLASMS, EXPERIMENTAL: Manual 24.5+, 24.6+; coordinate IM with histological type of neoplasm (IM)