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Bromocriptine
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Definition of 'Bromocriptine'

A semisynthetic ergotamine alkaloid that is a dopamine D2 agonist. It suppresses prolactin secretion.

Common names: Bromocriptine; 2-Bromo-alpha-ergokryptine; 2 Bromo alpha ergokryptine; Bromocryptin; 2-Bromoergokryptine; 2 Bromoergokryptine; Bromocriptin; 2-Bromoergocryptine; 2 Bromoergocryptine; 2-Bromo-alpha-ergocryptine; 2 Bromo alpha ergocryptine; 2-Bromoergocryptine Mesylate; 2 Bromoergocryptine Mesylate

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Monday, November 23, 2009

[Treatment of pituitary adenomas]

25 Sep 2009 According to epidemiological studies, the prevalence of pituitary adenomas is 16.5% and the majority of them are "incidentalomas". The symptoms of pituitary disorders are often non-specific; disturbances of pituitary function, compression symptoms, ... Read more...


Bromocriptine induces parapoptosis as the main type of cell death responsible for experimental pituitary tumor shrinkage.

8 Jul 2009 Bromocriptine (Bc) produces pituitary tumoral mass regression which induces the cellular death that was classically described as apoptosis. However, recent works have related that other mechanisms of cell death could also be involved in the ... Read more...


Serotonergic and dopaminergic modulation of gambling behavior as assessed using a novel rat gambling task.

15 Jun 2009 Pathological gambling (PG) is characterized by persistent, maladaptive gambling behavior, which disrupts personal and professional life. Animal models of gambling behavior could make a significant contribution to improving our understanding of the ... Read more...

 

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Technical information about 'Bromocriptine'

Definition: A semisynthetic ergotamine alkaloid that is a dopamine D2 agonist. It suppresses prolactin secretion.

Chemical name: Ergotaman-3',6',18-trione, 2-bromo-12'-hydroxy-2'-(1-methylethyl)-5'alpha-(2-methylpropyl)-

Registry Number: 25614-03-3

Descriptor UI: D001971

Alternative terms: Bromocriptine; 2-Bromo-alpha-ergokryptine; 2 Bromo alpha ergokryptine; Bromocryptin; 2-Bromoergokryptine; 2 Bromoergokryptine; Bromocriptin; 2-Bromoergocryptine; 2 Bromoergocryptine; 2-Bromo-alpha-ergocryptine; 2 Bromo alpha ergocryptine; 2-Bromoergocryptine Mesylate; 2 Bromoergocryptine Mesylate; Mesylate, 2-Bromoergocryptine; Bromocriptine Mesylate; Mesylate, Bromocriptine; 2-Bromoergocryptine Methanesulfonate; 2 Bromoergocryptine Methanesulfonate; Methanesulfonate, 2-Bromoergocryptine; CB-154; CB 154; CB154; Parlodel;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Antiparkinson Agents; Hormone Antagonists; Dopamine Agonists;

Tree Number: D03.132.327.412.100; D03.549.439.131; D03.549.562.100;

Online Note: use BROMOCRIPTINE to search 2-BROMOERGOCRYPTINE 1975-80

History Note: 81; was 2-BROMOERGOCRYPTINE 1978-80, was 2-BROMOERGOCRYPTINE see under ERGOTOXINE 1977, was 2-BROMOERGOCRYPTINE see under ERGOLINES 1975-76

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