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Buffers
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Definition of 'Buffers'

A chemical system that functions to control the levels of specific ions in solution. When the level of hydrogen ion in solution is controlled the system is called a pH buffer.

Common names: Buffers; Ampholytes

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Monday, November 23, 2009

Thermodynamic characterization of the interaction between the C-terminal domain of extracellular superoxide dismutase and heparin by isothermal titration calorimetry.

18 Oct 2009 Extracellular superoxide dismutase (ECSOD) interacts with heparin through its C-terminal domain. In this study we used isothermal titration calorimetry (ITC) to get detailed thermodynamic information about the interaction. We have shown that the ... Read more...


19F NMR studies of alpha-synuclein conformation and fibrillation.

13 Sep 2009 Fibrils of the intrinsically disordered protein alpha-synuclein are hallmarks of Parkinson's disease. The fluorescent dye thioflavin T is often used to characterize fibrillation, but this assay may not provide quantitative information about ... Read more...


Snapshots of the fluorosalinosporamide/20S complex offer mechanistic insights for fine tuning proteasome inhibition.

8 Sep 2009 Many marketed drugs contain fluorine, reflecting its ability to modulate a variety of biological responses. The unique 20S proteasome inhibition profile of fluorosalinosporamide compared to chlorinated anticancer agent salinosporamide A (NPI-0052) ... Read more...

 

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Technical information about 'Buffers'

Definition: A chemical system that functions to control the levels of specific ions in solution. When the level of hydrogen ion in solution is controlled the system is called a pH buffer.

Registry Number: 0

Descriptor UI: D002021

Alternative terms: Buffers; Ampholytes;

Tree Number: D27.720.470.280;

History Note: 67(64)

Technical Notes: almost never IM

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