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Caffeine - Administration & dosage
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Definition of 'Caffeine'

A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling.

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Sunday, November 22, 2009

Regulation of cerebrospinal fluid production by caffeine consumption.

Sep 2009 BACKGROUND: Caffeine is the most commonly consumed psycho-stimulant in the world. The effects of caffeine on the body have been extensively studied; however, its effect on the structure of the brain has not been investigated to date. RESULTS: In the ... Read more...


Caffeine, artificial sweetener, and fluid intake in anorexia nervosa.

30 Aug 2009 OBJECTIVE: This article provides an analysis of the use of artificial sweeteners, caffeine, and excess fluids in patients diagnosed with anorexia nervosa (AN). METHOD: Seventy participants with AN were recruited to participate in an ecologic ... Read more...


[Physical activity and dietary supplements]

15 Aug 2009 The Danish Fitness and Nutrition Council has examined the scientific literature to evaluate the performance and health-related aspects of consuming dietary supplements in the context of physical activity. Certain nutritional supplements such as ... Read more...

 

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Technical information about 'Caffeine'

Definition: A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling.

Chemical name: 1H-Purine-2,6-dione, 3,7-dihydro-1,3,7-trimethyl-

Registry Number: 58-08-2

Descriptor UI: D002110

Alternative terms: Caffeine; 1,3,7-Trimethylxanthine; Coffeinum N; Merck dura Brand of Caffeine; Coffeinum Purrum; Berlin-Chemie Brand of Caffeine; Dexitac; Republic Drug Brand of Caffeine; Vivarin; GlaxoSmithKline Brand of Caffeine; No Doz; Bristol-Myers Squibb Brand of Caffeine; Percoffedrinol N; Passauer Brand of Caffeine; Percutaféine; Pierre Fabre Brand of Caffeine; Quick-Pep; Thompson Brand 2 of Caffeine; Caffedrine; Thompson Brand 1 of Caffeine; Durvitan; Seid Brand of Caffeine;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Phosphodiesterase Inhibitors; Central Nervous System Stimulants;

Tree Number: D03.132.960.175; D03.438.759.758.824.175;

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