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Caffeine - Adverse effects
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Definition of 'Caffeine'

A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling.

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Saturday, November 21, 2009

Caffeine's implications for women's health and survey of obstetrician-gynecologists' caffeine knowledge and assessment practices.

30 Aug 2009 OBJECTIVE: Caffeine has relevance for women's health and pregnancy, including significant associations with spontaneous abortion and low birth weight. According to scientific data, pregnant women and women of reproductive age should be advised to ... Read more...


Caffeine expectancy: instrument development in the Rasch measurement framework.

30 Aug 2009 Although caffeine is the most widely consumed psychoactive drug in the world, the mechanisms associated with consumption are not well understood. Nonetheless, outcome expectancies for caffeine use are thought to underlie caffeine's reinforcing ... Read more...


Panic disorder and social anxiety disorder subtypes in a caffeine challenge test.

18 Aug 2009 Studies have demonstrated the vulnerability of anxiety disorder patients to challenge tests. Our aim was to observe if panic disorder (PD) patients and generalized social anxiety disorder (GSAD) and performance social anxiety disorder (PSAD) ... Read more...

 

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Technical information about 'Caffeine'

Definition: A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling.

Chemical name: 1H-Purine-2,6-dione, 3,7-dihydro-1,3,7-trimethyl-

Registry Number: 58-08-2

Descriptor UI: D002110

Alternative terms: Caffeine; 1,3,7-Trimethylxanthine; Coffeinum N; Merck dura Brand of Caffeine; Coffeinum Purrum; Berlin-Chemie Brand of Caffeine; Dexitac; Republic Drug Brand of Caffeine; Vivarin; GlaxoSmithKline Brand of Caffeine; No Doz; Bristol-Myers Squibb Brand of Caffeine; Percoffedrinol N; Passauer Brand of Caffeine; Percutaféine; Pierre Fabre Brand of Caffeine; Quick-Pep; Thompson Brand 2 of Caffeine; Caffedrine; Thompson Brand 1 of Caffeine; Durvitan; Seid Brand of Caffeine;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Phosphodiesterase Inhibitors; Central Nervous System Stimulants;

Tree Number: D03.132.960.175; D03.438.759.758.824.175;

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