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Calcification, Physiologic - Physiology
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Definition of 'Calcification, Physiologic'

Process by which organic tissue becomes hardened by the physiologic deposit of calcium salts.

Common names: Calcification, Physiologic; Calcification, Physiological; Physiological Calcification; Physiologic Calcification; Bone Mineralization; Mineralization, Bone

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Sunday, November 22, 2009

Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1).

29 Nov 2009 Osteosarcomas are the most prevalent primary bone tumors found in pediatric patients. To understand their molecular etiology, cell culture models are used to define disease mechanisms under controlled conditions. Many osteosarcoma cell lines (e.g., ... Read more...


Mineralized tissue formation by BMP2-transfected pulp stem cells.

30 Oct 2009 Previously, in vitro differentiation of odontoblasts was shown for dental pulp stem cells (DPSCs) transfected with bone morphogenetic protein-2 (Bmp2). For this study, we hypothesized that such cells also show potential for mineralized tissue ... Read more...


Asporin competes with decorin for collagen binding, binds calcium and promotes osteoblast collagen mineralization.

12 Sep 2009 The interactions of the ECM (extracellular matrix) protein asporin with ECM components have previously not been investigated. Here, we show that asporin binds collagen type I. This binding is inhibited by recombinant asporin fragment LRR ... Read more...

 

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Technical information about 'Calcification, Physiologic'

Definition: Process by which organic tissue becomes hardened by the physiologic deposit of calcium salts.

Descriptor UI: D002113

Alternative terms: Calcification, Physiologic; Calcification, Physiological; Physiological Calcification; Physiologic Calcification; Bone Mineralization; Mineralization, Bone;

Related Mesh Headings: Bone Development; Osteogenesis;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects;

Tree Number: G07.700.320.186; G07.700.320.500.325.377.625.100.175; G11.427.590.560.100.175;

History Note: 65; was CALCIFICATION 1963-64

Technical Notes: TOOTH CALCIFICATION is also available; DF: CALCIFICATION PHYSIOL

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